Paraneoplastic vasculitis associated with multiple myeloma

被引:20
作者
Sánchez, NB [1 ]
Canedo, IF [1 ]
García-Patos, PE [1 ]
Pérez, PD [1 ]
Benito, AV [1 ]
Pascual, AM [1 ]
机构
[1] Univ Hosp Salamanca, Dept Dermatol, Salamanca, Spain
关键词
leucocytoclastic vasculitis; multiple myeloma; paraneoplastic vasculitis;
D O I
10.1111/j.1468-3083.2004.01069.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The association between vasculitis and cancer has been widely reviewed in recent decades. The existence of malignancies in patients with vasculitis has been estimated at about 4.5-8%, haematological neoplasms being the most frequently observed. The haematological malignancies most frequently described are lympho-proliferative diseases such as hairy cell leukaemia and lymphomas. On the contrary, the incidence of paraneoplastic vasculitis in patients with myeloma is low; up to now, we have found nine cases reported on this subject. We report the case of a 73-year-old woman who in 1 year showed three outbreaks of acutely painful, purpuric and ulceronecrotic lesions, localized on the lower extremities. Histopathological study demonstrated thrombosis in the arterioles and leucocytoclastic vasculitis. Complementary tests revealed the presence of multiple myeloma.
引用
收藏
页码:731 / 735
页数:5
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