Racial disparities in pediatric kidney transplantation in New Zealand

被引:21
作者
Grace, Blair S. [1 ,2 ]
Kara, Tonya [3 ]
Kennedy, Sean E. [4 ,5 ]
McDonald, Stephen P. [1 ,2 ]
机构
[1] Australia & New Zealand Dialysis & Transplant Reg, Adelaide, SA, Australia
[2] Univ Adelaide, Discipline Med, Adelaide, SA, Australia
[3] Starship Childrens Hlth, Auckland, New Zealand
[4] Sydney Childrens Hosp, Dept Nephrol, Randwick, SA, Australia
[5] Univ New S Wales, Sch Womens & Childrens Hlth, Sydney, NSW, Australia
关键词
Maori; Pacific people; organ donation; live donor; Australia and New Zealand Dialysis and Transplant Registry; PACIFIC ISLAND; DISEASE; CHILDREN; ACCESS; MAORI; AUSTRALIA; SURVIVAL; DIALYSIS;
D O I
10.1111/petr.12322
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Racial disparities in transplantation rates and outcomes have not been investigated in detail for NZ, a country with unique demographics. We studied a retrospective cohort of 215 patients <18yr who started renal replacement therapy in NZ 1990-2012, using the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). Primary outcomes were time to first kidney transplant, death-censored graft survival, and retransplantation after loss of primary graft. Europeans and Asians were most likely to receive a transplant (92% and 91% transplanted within fiveyr, respectively), and Pacific and Maori patients were less likely to receive a transplant than Europeans (51% and 46%, respectively), reflecting disparities in live donor transplantation. Pacific patients were more likely to have glomerulonephritis and FSGS. Pacific patients had five-yr death-censored graft survival of 31%, lower than Maori (61%) and Europeans (88%). No Pacific patients who lost their grafts were re-transplanted within 72 patient-years of follow-up, whereas 14% of Maori patients and 36% of European and Asian patients were retransplanted within fiveyr. Current programs to improve live and deceased donation within Maori and Pacific people and management of recurrent kidney disease are likely to reduce these disparities.
引用
收藏
页码:689 / 697
页数:9
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