Biocide Use in the Antimicrobial Era: A Review

被引:129
作者
Jones, Imogen Anne [1 ]
Joshi, Lovleen Tina [1 ]
机构
[1] Univ Plymouth, Sch Biomed Sci, Plymouth PL4 8AA, Devon, England
关键词
biocides; bacteria; antibiotic; antimicrobial; disinfection; surfaces; transmission; chemical; resistance; HYDROGEN-PEROXIDE; SODIUM DICHLOROISOCYANURATE; SURFACE DISINFECTION; BACTERIAL BIOCIDE; RESISTANCE; EFFICACY; MECHANISMS; HYPOCHLORITE; CHLORHEXIDINE; SAFETY;
D O I
10.3390/molecules26082276
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Biocides are widely used in healthcare and industry to control infections and microbial contamination. Ineffectual disinfection of surfaces and inappropriate use of biocides can result in the survival of microorganisms such as bacteria and viruses on inanimate surfaces, often contributing to the transmission of infectious agents. Biocidal disinfectants employ varying modes of action to kill microorganisms, ranging from oxidization to solubilizing lipids. This review considers the main biocides used within healthcare and industry environments and highlights their modes of action, efficacy and relevance to disinfection of pathogenic bacteria. This information is vital for rational use and development of biocides in an era where microorganisms are becoming resistant to chemical antimicrobial agents.
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页数:11
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