The quest for long non-coding RNAs involved in aging

被引：1
作者：
Avolio, Rosario [1 ]
Bechara, Elias [2 ]
Tartaglia, Gian Gaetano [2 ,3 ,4 ,5 ]
机构：
[1] Univ Naples Federico II, Dept Mol Med & Med Biotechnol, Naples, Italy
[2] Ist Italiano Tecnol, Ctr Human Technol, Genoa, Italy
[3] Sapienza Univ Rome, Dept Biol & Biotechnol Charles Darwin, Rome, Italy
[4] Ist Italiano Tecnol, Ctr Life Nano& Neurosci, Rome, Italy
[5] Institucio Catalana Recerca & Estudis Avancats ICR, Barcelona, Spain
来源：
NATURE AGING | 2021年 / 1卷 / 05期
基金：
欧洲研究理事会;
关键词：
SENESCENT CELLS; TARGETS; SASP;
D O I：
10.1038/s43587-021-00069-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Chronic inflammation, or 'inflammaging', is a key process in age-related diseases, and identification of the molecular players involved is a top priority. Cai and Han identified an evolutionary conserved functional lncRNA able to modulate the release of inflammatory SASP molecules from senescent cells through the NF-kappa B pathway.
引用
收藏
页码：418 / 419
页数：2
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