Blink-sensing glasses: A flexible iontronic sensing wearable for continuous blink monitoring

被引:18
作者
Chen, Rui [1 ,2 ]
Zhang, Zhichao [3 ,6 ]
Deng, Ka [1 ,7 ]
Wang, Dahu [4 ]
Ke, Hongmin [5 ]
Cai, Li [5 ]
Chang, Chi-wei [1 ]
Pan, Tingrui [1 ,3 ,7 ,8 ,9 ]
机构
[1] Chinese Acad Sci, Inst Biomed & Hlth Engn, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China
[2] Univ Chinese Acad Sci, Sch Comp Sci, Beijing 100049, Peoples R China
[3] Univ Calif Davis, Dept Biomed Engn, Micronano Innovat MiNI Lab, Davis, CA 95616 USA
[4] Shanghai Univ Tradit Chinese Med, Dept Ophthalmol, LongHua Hosp, Shanghai 200032, Peoples R China
[5] Shenzhen Univ, Dept Ophthalmol, Gen Hosp, Clin Med Acad, Shenzhen 518055, Peoples R China
[6] TacSense Inc, Woodland, CA 95776 USA
[7] Shenzhen Engn Lab Single Mol Detect & Instrument, Shenzhen 518055, Peoples R China
[8] Univ Sci & Technol China, Suzhou Inst Adv Res, Suzhou 215123, Peoples R China
[9] Univ Sci & Technol China, Dept Precis Machinery & Precis Instrumentat, Hefei 230026, Peoples R China
基金
中国国家自然科学基金;
关键词
DRY; PRESSURE; SYSTEM; TIME; FILM; EMG;
D O I
10.1016/j.isci.2021.102399
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Blink reflex has long been considered closely related to physiological states, from which abundant information on ocular health and activities can be revealed. In this study, a smart glasses wearable has been developed, incorporating a flexible and sensitive pressure sensor, to monitor blink patterns by continuously detecting ocular muscular movements, referred to as blink-sensing glasses. By applying the emerging flexible iontronic sensing (FITS) sensor with the sensitivity of 340 pF/mmHg, the skin pressure variations induced by movements of the orbicularis oculimuscles can be monitored in real time. The blink-sensing glasses can successfully capture blink patterns with a high accuracy of 96.3% and have been used to differentiate the blink features from both dry-eye subjects and healthy controls. This device can be potentially used as a new clinical and research monitoring tool for continuous eye blink analysis, while providing patients with high comfortableness in long-term ambulatory and home settings.
引用
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页数:24
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