Botulinum Toxin Type A Reconstituted with Lidocaine: A Report of 1000 Consecutive Cases

被引:1
作者
Bove, Pierfrancesco [1 ]
Santillo, Vincenzo [2 ]
Colella, Giuseppe [2 ]
Vitagliano, Rita [2 ]
Fragola, Romolo [2 ]
Lo Giudice, Giorgio [3 ]
Zerbinati, Nicola [4 ]
Ferrieri, Ivo [2 ]
Rauso, Raffaele [2 ]
机构
[1] Aesthet Surg Private Practice, Chirurg Bellezza, Via Melisurgo 4, I-80138 Naples, Italy
[2] Univ Campania Luigi Vanvitelli, Oral & Maxillofacial Surg Unit, Multidisciplinary Dept Med Surg & Dent Specialtie, Via Luigi De Crecchio 6, I-80138 Naples, Italy
[3] Univ Naples Federico II, Maxillofacial Surg Unit, Dept Neurosci Reprod & Odontostomatol Sci, Via Pansini 5, I-80131 Naples, Italy
[4] Univ Insubria, Dermatol Dept, Via Guicciardini 9, I-21100 Varese, Italy
来源
APPLIED SCIENCES-BASEL | 2021年 / 11卷 / 10期
关键词
botulinum toxin; facial aesthetics; minimally invasive; lidocaine; 2 COMMERCIAL PREPARATIONS; DOUBLE-BLIND; AXILLARY HYPERHIDROSIS; AESTHETIC MEDICINE; NORMAL SALINE; LINES; FORMULATIONS; NECK;
D O I
10.3390/app11104491
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(1) Background: There is an increasing demand for a reversal of the aging process and, nowadays, more patients are seeking minimally invasive methods instead of surgery to meet this goal. The purpose of this paper is to evaluate the predictability of the off-label aesthetic use of botulinum toxin type A (BoNTA) reconstituted with lidocaine. (2) Methods: One thousand treatments, between January 2010 and January 2020, with BoNTA reconstituted with lidocaine for the rejuvenation of the upper third of the face, were performed and retrospectively evaluated. (3) Results: A few seconds after the BoNTA injections, the effect of muscle paralysis was seen in all cases; this allowed providing an optimal symmetric result with no need for a touch-up procedure at the control after three weeks. A burning sensation during the injections was claimed by almost all patients. Major complications were not registered. No touch-up procedures were required. (4) Conclusions: The results of this study show how the reconstitution of BoNTA with lidocaine may avoid imperfect results after the injections; the immediate feedback on the extent of paralysis to be expected from the chemodenervation action of BoNTA allows the physician to have immediate control of the final result.
引用
收藏
页数:8
相关论文
共 37 条
[1]  
AIFA, FOG ILL INF UT AZZ
[2]  
AIFA, FOGL ILL INF UT BOTO
[3]   Using translational medicine to understand clinical differences between botulinum toxin formulations [J].
Aoki, K. R. ;
Ranoux, D. ;
Wissel, J. .
EUROPEAN JOURNAL OF NEUROLOGY, 2006, 13 :10-19
[4]  
Brin M.F., 2018, BOTULINUM TOXINS CLI, V3rd ed.
[5]   ASSAY OF DIFFUSION OF DIFFERENT BOTULINUM NEUROTOXIN TYPE A FORMULATIONS INJECTED IN THE MOUSE LEG [J].
Carli, Luca ;
Montecucco, Cesare ;
Rossetto, Ornella .
MUSCLE & NERVE, 2009, 40 (03) :374-380
[6]   TREATMENT OF GLABELLAR FROWN LINES WITH C-BOTULINUM-A EXOTOXIN [J].
CARRUTHERS, JDA ;
CARRUTHERS, JA .
JOURNAL OF DERMATOLOGIC SURGERY AND ONCOLOGY, 1992, 18 (01) :17-21
[7]   Effective Locations for Injecting Botulinum Toxin into the Mentalis Muscle; Cadaveric and Ultrasonographic Study [J].
Choi, Da-Yae ;
Bae, Hyungkyu ;
Bae, Jung-Hee ;
Kim, Hee-Jin ;
Hu, Kyung-Seok .
TOXINS, 2021, 13 (02)
[8]  
Cliff Sandeep H, 2008, J Cosmet Dermatol, V7, P50, DOI 10.1111/j.1473-2165.2008.00361.x
[9]  
De Maio M., 2007, BOTULINUM TOXIN AEST, DOI [10.1007/978-3-540-34095-9, DOI 10.1007/978-3-540-34095-9]
[10]   Botulinum Toxin in Aesthetic Medicine: Myths and Realities [J].
Dover, Jeffrey S. ;
Monheit, Gary ;
Greener, Mark ;
Pickett, Andy .
DERMATOLOGIC SURGERY, 2018, 44 (02) :249-260