Functional components, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of Salvia syriaca L.

被引：65

作者：

Bahadori, Mir Babak ^{[1
]}

Dinparast, Leila ^{[2
]}

Zengin, Gokhan ^{[3
]}

Sarikurkcu, Cengiz ^{[4
]}

Bahadori, Shahram ^{[5
]}

Asghari, Behvar ^{[6
]}

Movahhedin, Nasrin ^{[5
]}

机构：

[1] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[2] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz, Iran

[3] Selcuk Univ, Sci Fac, Dept Biol, Konya, Turkey

[4] Suleyman Demirel Univ, Fac Pharm, Dept Analyt Chem, Isparta, Turkey

[5] Urmia Univ Med Sci, Fac Pharm, Dept Pharmacognosy, Nazloo St, Orumiyeh, Iran

[6] Imam Khomeini Int Univ, Fac Engn & Technol, Dept Plant Prod & Breeding Engn, Qazvin, Iran

来源：

INTERNATIONAL JOURNAL OF FOOD PROPERTIES | 2017年 / 20卷 / 08期

关键词：

Salvia syriaca; Alzheimer's; disease; Diabetes mellitus; Phenolic compounds; Rutin; Spathulenol; IN-VITRO ANTIOXIDANT; ENZYME-INHIBITORY ACTIVITIES; PHENOLIC CONTENTS; ESSENTIAL OIL; URMIENSIS BUNGE; AERIAL PARTS; TRITERPENOIDS; CONSTITUENTS; RUTIN; TURKEY;

D O I：

10.1080/10942912.2016.1218893

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Antidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, a-amylase, and a-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.

引用

页码：1761 / 1772

页数：12

共 47 条

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