Three Cases of Intravascular Large B-Cell Lymphoma Detected in a Biopsy of Skin Lesions

被引：20
作者：
Arai, Takashi [1 ,2 ]
Kato, Yukihiko [1 ,2 ]
Funaki, Maki [3 ]
Shimamura, Sanae [4 ]
Yokogawa, Naoto [4 ]
Sugii, Syoji [4 ]
Tsuboi, Ryoji [5 ]
机构：
[1] Tokyo Metropolitan Tama Med Ctr, Dept Dermatol, Fuchu, Tokyo 1838524, Japan
[2] Tokyo Med Univ, Tokyo 1608402, Japan
[3] Tokyo Med Univ, Dept Hematol, Tokyo 1608402, Japan
[4] Tokyo Med Univ, Dept Rheumatol, Tokyo 1608402, Japan
[5] Tokyo Med Univ, Dept Dermatol, Tokyo 1608402, Japan
来源：
DERMATOLOGY | 2016年 / 232卷 / 02期
关键词：
Intravascular large B-cell lymphoma; Random skin biopsy; Skin lesion; ASIAN VARIANT; DIAGNOSIS;
D O I：
10.1159/000437363
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Intravascular large B-cell lymphoma (IVL) is a rare subtype of extranodal malignant lymphoma. The proliferation of neoplastic B cells within small blood vessels causes eruptions and other symptoms in a variety of organs. The random skin biopsy is useful for diagnosing this condition in its early stages. In order to assess the diagnostic utility of this method, we examined 3 cases with the aim of comparing the occurrence of tumor cells in lesional and healthy-looking skin by performing a random skin biopsy of 32 separate sites. Our findings from the total of 32 biopsy specimens collected from the 3 cases indicated that 16 of the 17 sites on the lesional skin and 1 of the 15 sites on the healthy-looking skin were positive for neoplastic cells. This finding suggested that IVL cells occurred more frequently in the lesional skin than in the healthy-looking skin. (C) 2016 S. Karger AG, Basel
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收藏
页码：185 / 188
页数：4
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