3D-printed miniaturized fluidic tools in chemistry and biology

被引:55
作者
Dixit, C. K. [1 ]
Kadimisetty, K. [1 ]
Rusling, J. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA
[2] Univ Connecticut, Inst Mat Sci, Storrs, CT 06269 USA
[3] UConn Hlth, Dept Surg, Farmington, CT 06030 USA
[4] UConn Hlth, Neag Canc Ctr, Farmington, CT 06030 USA
[5] Natl Univ Ireland Galway, Sch Chem, Galway, Ireland
关键词
3D printing; Additive manufacturing; Microfluidics; Lab-on-a-chip; DLP; SLA; SLS; MultiJet; FDM; ON-A-CHIP; CIRCULATING TUMOR-CELLS; PRINTED MICROFLUIDIC DEVICES; REAL-TIME; HIGH-THROUGHPUT; INTEGRATED BIOSENSORS; 3D; FABRICATION; CULTURE; POLYMER;
D O I
10.1016/j.trac.2018.06.013
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
3D printing (3DP), an additive manufacturing (AM) approach allowing for rapid prototyping and decentralized fabrication on-demand, has become a common method for creating parts or whole devices. The wide scope of the AM extends from organized sectors of construction, ornament, medical, and R&D industries to individual explorers attributed to the low cost, high quality printers along with revolutionary tools and polymers. While progress is being made but big manufacturing challenges are still there. Considering the quickly shifting narrative towards miniaturized analytical systems (MAS) we focus on the development/rapid prototyping and manufacturing of MAS with 3DP, and application dependent challenges in engineering designs and choice of the polymeric materials and provide an exhaustive background to the applications of 3DP in biology and chemistry. This will allow readers to perceive the most important features of AM in creating (i) various individual and modular components, and (ii) complete integrated tools. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:37 / 52
页数:16
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