Osimertinib in EGFR T790M Advanced NSCLC: Analysis of Uncommon/Complex EGFR Mutations in a Real-World Study (ASTRIS)

被引:4
作者
Cheema, P. [1 ]
Passaro, A. [2 ]
Martin, C. [3 ]
Tiseo, M. [4 ]
Park, K. [5 ]
Chang, G. [6 ,7 ,8 ]
Hu, Y. [9 ]
Cho, B. C. [10 ]
Miranda, M. [11 ]
Fernandes, A. [12 ]
Freitas, H. [13 ]
机构
[1] Univ Toronto, Sunnybrook Odette Canc Ctr, William Osler Hlth Syst, Toronto, ON, Canada
[2] European Inst Oncol Irccs, Ieo, Div Thorac Oncol, Milan, Italy
[3] Inst Alexander Fleming, Dept Oncol, Buenos Aires, DF, Argentina
[4] Univ Hosp Parma, Med Oncol Unit, Parma, Italy
[5] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Hematol Oncol, Seoul, South Korea
[6] Taichung Vet Gen Hosp, Dept Internal Med, Div Chest Med, Taichung, Taiwan
[7] Taichung Vet Gen Hosp, Fac Med, Sch Med, Taichung, Taiwan
[8] Natl Yang Ming Univ, Taichung, Taiwan
[9] Hubei Canc Hosp, Dept Oncol, Wuhan, Hubei, Peoples R China
[10] Yonsei Univ, Coll Med, Yonsei Canc Ctr, Seoul, South Korea
[11] Astrazeneca, Biometr & Informat Sci, Cambridge, England
[12] Astrazeneca Us, Gaithersburg, MD USA
[13] AC Camargo Canc Ctr, Clin Res Unit, Sao Paulo, Brazil
关键词
NSCLC; EGFR; Osimertinib;
D O I
10.1016/j.jtho.2019.08.1844
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P2.14-59
引用
收藏
页码:S854 / S854
页数:1
相关论文
共 50 条
  • [41] EGFR T790M mutation testing within the osimertinib AURA Phase I study
    Dearden, Simon
    Brown, Helen
    Jenkins, Suzanne
    Thress, Kenneth S.
    Cantarini, Mireille
    Cole, Rebecca
    Ranson, Malcolm
    Janne, Pasi A.
    LUNG CANCER, 2017, 109 : 9 - 13
  • [42] Different Responses to Osimertinib in Primary and Acquired EGFR T790M-Mutant NSCLC Patients
    Wang, S.
    Zhang, B.
    Han, B.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S409 - S409
  • [43] Real-World EGFR T790M Testing in Advanced Non-Small-Cell Lung Cancer: A Prospective Observational Study in Japan
    Takashi Seto
    Naoyuki Nogami
    Nobuyuki Yamamoto
    Shinji Atagi
    Naoki Tashiro
    Yoko Yoshimura
    Yutaka Yabuki
    Hideo Saka
    Oncology and Therapy, 2018, 6 (2) : 203 - 215
  • [44] Detection of EGFR T790M Mutations by Four Testing Platforms in ctDNA from Chinese Patients with Advanced NSCLC
    Zhang, X.
    Liang, Z.
    Chen, Y.
    Zhang, H.
    Wu, G.
    Lu, Y.
    Liang, Z.
    Cheng, Y.
    Hu, Y.
    Wang, J.
    Ying, J.
    Liu, W.
    Wu, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (11) : S1823 - S1823
  • [45] Analyses of CNS Response to Osimertinib in Patients with T790M-Positive Advanced NSCLC from ASTRIS Korean Subset, Open-Label Real-World Study
    Ahn, Beung-Chul
    Kim, Jee Hung
    Pyo, Kyoung-Ho
    Lim, Sun Min
    Hong, Min Hee
    Kim, Hye Ryun
    Cho, Byoung Chul
    CANCERS, 2021, 13 (15)
  • [46] Glioblastoma with novel EGFR mutations (T790M and exon 20 insertion) yet unresponsive to osimertinib: A case report
    Boongird, Atthaporn
    Lekcharoensombat, Nopphon
    Jinawath, Artit
    Theparee, Talent
    Jittapiromsak, Nutchawan
    Shuangshoti, Shanop
    Thorner, Paul Scott
    Teerapakpinyo, Chinachote
    GENES CHROMOSOMES & CANCER, 2023, 62 (07) : 423 - 429
  • [47] Reduced sensitivity for EGFR T790M mutations using the Idylla EGFR Mutation Test
    Lee, Eric
    Jones, Victoria
    Topkas, Eleni
    Harraway, James
    JOURNAL OF CLINICAL PATHOLOGY, 2021, 74 (01) : 43 - 47
  • [48] EGFR T790M testing through repeated liquid biopsy over time: a real-world multicentric retrospective experience
    Dal Maso, Alessandro
    Del Bianco, Paola
    Cortiula, Francesco
    Nardo, Giorgia
    Zulato, Elisabetta
    Bonanno, Laura
    Follador, Alessandro
    De Maglio, Giovanna
    Pasello, Giulia
    Indraccolo, Stefano
    JOURNAL OF THORACIC DISEASE, 2022, 14 (09) : 3364 - +
  • [49] Detection of EGFR Mutations T790M and L858R for Therapeutic Guidance of NSCLC
    Rana, M.
    Asil, S. M.
    Boutin, C.
    Kachwala, M. J.
    Espejo, J.
    Argun, A. A.
    JOURNAL OF THORACIC ONCOLOGY, 2024, 19 (10) : S496 - S496
  • [50] Activity of OsimeRTInib in NSCLC with Uncommon EGFR Mutations: Retrospective Observational Multicenter Study (ARTICUNO)
    Pizzutilo, E. G.
    Agostara, A. G.
    Oresti, S.
    Signorelli, D.
    Giannetta, L. G.
    Stabile, S.
    Lauricella, C.
    Amatu, A.
    Brambilla, M.
    Lo Russo, G.
    Proto, C.
    Mazzeo, L.
    Beninato, T.
    Siringo, M.
    Giusti, R.
    Filetti, M.
    Genova, C.
    Barletta, G.
    Russano, M.
    Di Fazio, G. R.
    Tosoni, E.
    Metro, G.
    Pilotto, S.
    Carta, A.
    Mazzoni, F.
    Roca, E.
    Gelibter, A. J.
    Gori, S.
    Berardi, R.
    Cerea, G.
    Sartore-Bianchi, A.
    Siena, S.
    JOURNAL OF THORACIC ONCOLOGY, 2022, 17 (09) : S418 - S419