Natural History and Ecology of Interactions Between Bordetella Species and Amoeba

被引:6
|
作者
Ma, Longhuan [1 ]
Linz, Bodo [1 ,2 ]
Caulfield, Amanda D. [1 ]
Dewan, Kalyan K. [1 ]
Rivera, Israel [1 ]
Harvill, Eric T. [1 ]
机构
[1] Univ Georgia, Coll Vet Med, Dept Infect Dis, Athens, GA 30602 USA
[2] Friedrich Alexander Univ Erlangen Nuremberg, Div Microbiol, Dept Biol, Erlangen, Germany
来源
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2022年 / 12卷
基金
美国国家卫生研究院;
关键词
Bordetella species; Dictyostelium discoideum; interactions; evolution; GWAS -genome-wide association study; RESPIRATORY EPITHELIAL-CELLS; SP-NOV; INTRACELLULAR SURVIVAL; PERTUSSIS; INVASION; PHAGOCYTOSIS; INFECTIONS; SEQUENCES; TOXIN;
D O I
10.3389/fcimb.2022.798317
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent interactions with phagocytes in animal hosts. Our recent study found that the animal pathogen Bordetella bronchiseptica can evade predation by the common soil amoeba Dictyostelium discoideum, survive within, and hijack its complex life cycle as a propagation and dissemination vector. However, it is uncertain whether the mechanisms allowing interactions with predatory amoebae are conserved among Bordetella species, because divergence, evolution, and adaptation to different hosts and ecological niches was accompanied by acquisition and loss of many genes. Here we tested 9 diverse Bordetella species in three assays representing distinct aspects of their interactions with D. discoideum. Several human and animal pathogens retained the abilities to survive within single-celled amoeba, to inhibit amoebic plaque expansion, and to translocate with amoebae to the fruiting body and disseminate along with the fruiting body. In contrast, these abilities were partly degraded for the bird pathogen B. avium, and for the human-restricted species B. pertussis and B. parapertussis. Interestingly, a different lineage of B. parapertussis only known to infect sheep retained the ability to interact with D. discoideum, demonstrating that these abilities were lost in multiple lineages independently, correlating with niche specialization and recent rapid genome decay apparently mediated by insertion sequences. B. petrii has been isolated sporadically from diverse human and environmental sources, has acquired insertion sequences, undergone genome decay and has also lost the ability to interact with amoebae, suggesting some specialization to some unknown niche. A genome-wide association study (GWAS) identified a set of genes that are potentially associated with the ability to interact with D. discoideum. These results suggest that massive gene loss associated with specialization of some Bordetella species to a closed life cycle in a particular host was repeatedly and independently accompanied by loss of the ability to interact with amoebae in an environmental niche.
引用
收藏
页数:12
相关论文
共 50 条
  • [41] Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance
    Chan, Wai-Jo Jocelin
    Adiwidjaja, Jeffry
    McLachlan, Andrew J.
    Boddy, Alan V.
    Harnett, Joanna E.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2023, 91 (02) : 103 - 119
  • [42] Interactions Between Natural Products and Tamoxifen in Breast Cancer: A Comprehensive Literature Review
    Yen, Christine
    Zhao, Fan
    Yu, Zhichao
    Zhu, Xiaoshu
    Li, Chun Guang
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [43] In vitro interactions between several species of harmful algae and haemocytes of bivalve molluscs
    Hegaret, Helene
    da Silva, Patricia Mirella
    Wikfors, Gary H.
    Haberkorn, Hansy
    Shumway, Sandra E.
    Soudant, Philippe
    CELL BIOLOGY AND TOXICOLOGY, 2011, 27 (04) : 249 - 266
  • [44] Positive indirect interactions between neighboring plant species via a lizard pollinator
    Hansen, Dennis M.
    Kiesbuey, Heine C.
    Jones, Carl G.
    Mueller, Christine B.
    AMERICAN NATURALIST, 2007, 169 (04) : 534 - 542
  • [45] Plant-pollinator interactions: comparison between an invasive and a native congeneric species
    Vanparys, Valerie
    Meerts, Pierre
    Jacquemart, Anne-Laure
    ACTA OECOLOGICA-INTERNATIONAL JOURNAL OF ECOLOGY, 2008, 34 (03): : 361 - 369
  • [46] Mating system transitions in Solanum habrochaites impact interactions between populations and species
    Broz, Amanda K.
    Randle, April M.
    Sianta, Shelley A.
    Tovar-Mendez, Alejandro
    McClure, Bruce
    Bedinger, Patricia A.
    NEW PHYTOLOGIST, 2017, 213 (01) : 440 - 454
  • [47] Temperature influences species interactions between a native and a globally invasive freshwater snail
    Sardina, Paula
    Beringer, Jason
    Roche, Dylan
    Thompson, Ross M.
    FRESHWATER SCIENCE, 2015, 34 (03) : 933 - 941
  • [48] In vitro interactions between several species of harmful algae and haemocytes of bivalve molluscs
    Hélène Hégaret
    Patricia Mirella da Silva
    Gary H. Wikfors
    Hansy Haberkorn
    Sandra E. Shumway
    Philippe Soudant
    Cell Biology and Toxicology, 2011, 27 : 249 - 266
  • [49] Reproductive Ecology of Three Tibetan Waterbird Species, with Special Reference to Life-History Alterations along Elevational Gradients
    Lu, Xin
    ZOOLOGICAL STUDIES, 2011, 50 (02) : 192 - 202
  • [50] Hybrid Incompatibilities, Local Adaptation, and the Genomic Distribution of Natural Introgression between Species
    Muirhead, Christina A.
    Presgraves, Daven C.
    AMERICAN NATURALIST, 2016, 187 (02) : 249 - 261