Evaluation of gold layer configuration for plasmonic fiber grating biosensors

被引:50
作者
Caucheteur, C. [1 ]
Loyez, M. [2 ]
Gonzalez-Vila, A. [1 ]
Wattiez, R. [2 ]
机构
[1] Univ Mons, Electromagnetism & Telecommun Dept, Blvd Dolez 31, B-7000 Mons, Belgium
[2] Univ Mons, Prote & Microbiol Dept, Ave Champ de Mars 6, B-7000 Mons, Belgium
关键词
OPTICAL-FIBER; RESONANCE TECHNOLOGY; SENSORS; SENSITIVITY; REFRACTOMETER; EXCITATION; WATER;
D O I
10.1364/OE.26.024154
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Gold-coated fiber Bragg gratings (FBGs) are nowadays a mature technology for lab-on-fiber sensing based on surface plasmon resonance (SPR) excitation. Tilted FBGs bring valuable assets such as easy light injection, remote operation in very small volumes of analytes and immunity to temperature fluctuations. Different gold configurations have been reported to date. without considering their relative performances in terms of biochemical sensing. In this work, we experimentally study the impact of the gold coating on the cladding mode distribution in the tilted FBG amplitude spectrum and subsequently on its sensitivity to cytokeratins used as biomarkers for cancer diagnosis. Some relevant configurations of gold coatings are produced and tested. relying on both the sputtering and electroless plating (ELP) processes. The obtained results confirm that the coating thickness and its roughness drive the biosensing performances. The experimental limit of detection for cytokeratins 17 sensing reaches 14 fM for the most sensitive configurations. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码:24154 / 24163
页数:10
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