How Does a "Dry Tap" Impact the Accuracy of Preoperative Aspiration Results in Predicting Chronic Periprosthetic Joint Infection?

Background: Periprosthetic joint infection (PJI) after total hip arthroplasty (THA) is challenging to di-agnose. We aimed to evaluate the impact of dry taps requiring saline lavage during preoperative intra-articular hip aspiration on the accuracy of diagnosing PJI before revision surgery. Methods: A retrospective review was conducted for THA patients with suspected PJI who received an image-guided hip aspiration from May 2016 to February 2020. Musculoskeletal Infection Society (MSIS) diagnostic criteria for PJI were compared between patients who had dry tap (DT) vs successful tap (ST). Sensitivity and specificity of synovial markers were compared between the DT and ST groups. Concor-dance between preoperative and intraoperative cultures was determined for the 2 groups. Results: In total, 335 THA patients met inclusion criteria. A greater proportion of patients in the ST group met MSIS criteria preoperatively (30.2% vs 8.3%, P < .001). Patients in the ST group had higher rates of revision for PJI (28.4% vs 17.5%, P = .026) and for any indication (48.4% vs 36.7%, P = .039). MSIS synovial white blood cell count thresholds were more sensitive in the ST group (90.0% vs 66.7%). There was no difference in culture concordance (67.9% vs 65.9%, P = .709), though the DT group had a higher rate of negative preoperative cultures followed by positive intraoperative cultures (85.7% vs 41.1%, P = .047). Conclusion: Our results indicate that approximately one third of patients have dry hip aspiration, and in these patients cultures are less predictive of intraoperative findings. This suggests that surgeons considering potential PJI after THA should apply extra scrutiny when interpreting negative results in patients who require saline lavage for hip joint aspiration. (c) 2022 Elsevier Inc. All rights reserved.