Catalyst-free one-pot synthesis of benzimidazoles from 1,2-diaminoarenes and alcohols

被引：18

作者：

Marri, Mahender Reddy ^{[1
]}

Peraka, Swamy ^{[1
]}

Macharla, Arun Kumar ^{[1
]}

Mameda, Naresh ^{[1
]}

Kodumuri, Srujana ^{[1
]}

Nama, Narender ^{[1
]}

机构：

[1] CSIR Indian Inst Chem Technol, I & PC Div, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 48期

关键词：

Aryl alcohols; Amines; Benzimidazoles; Environmentally-benign; Atom economy; HIV-1; REVERSE-TRANSCRIPTASE; 2-SUBSTITUTED BENZIMIDAZOLES; NONNUCLEOSIDE INHIBITORS; BIOLOGICAL-ACTIVITY; EFFICIENT; IMIDAZOLINES; HETEROCYCLES; BENZAZOLES; DISCOVERY; ANALOGS;

D O I：

10.1016/j.tetlet.2014.09.081

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and efficient protocol is described for the aryl alcohols and 1,2-diaminoarenes. The yields the present method is utilizing alcohols instead solvent- and catalyst-free conditions, offering an one-pot synthesis of benzimidazoles from a variety of were ranging from moderate to excellent. Moreover, of aldehydes and the reactions are carried out under environmentally benign process. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：6520 / 6525

页数：6

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