Subclinical Carotid Atherosclerosis in Asymptomatic Subjects With Type 2 Diabetes Mellitus

被引：14

作者：

Rubinat, Esther ^{[1
,2
]}

Ramon Marsal, Josep ^{[3
,4
]}

Vidal, Teresa ^{[5
,6
]}

Cebrian, Cristina ^{[7
]}

Falguera, Mireia ^{[8
]}

Belen Vilanova, Ma. ^{[8
]}

Betriu, Angels ^{[5
,6
]}

Fernandez, Elvira ^{[5
,6
]}

Franch, Josep ^{[9
,10
]}

Mauricio, Didac ^{[5
,10
,11
]}

机构：

[1] Hosp Arnau Vilanova, Dept Endocrinol & Nutr, Lleida, Spain

[2] Univ Lleida, Inst Recerca Biomed Lleida, Lleida, Spain

[3] Inst Univ Invest Atencio Primaria Jordi Gol IDIA, Unitat Suport Recerca Lleida, Lleida, Spain

[4] Hosp Univ Vall dHebron, Serv Cardiol, Unitat Epidemiol, Barcelona, Spain

[5] Hosp Arnau Vilanova, Unitat Deteccio & Tractament Malalties Aterotromb, Lleida, Spain

[6] Hosp Arnau Vilanova, Dept Nephrol, Lleida, Spain

[7] Primary Hlth Care Ctr Primer Maig, Lleida, Spain

[8] Primary Hlth Care Ctr Igualada Nord, Vigo, Spain

[9] Primary Hlth Care Ctr Raval Sud, Barcelona, Spain

[10] Inst Univ Invest Atencio Primaria Jordi Gol, Barcelona, Spain

[11] Hosp Germans Trias Pujol, Dept Endocrinol & Nutr, Carretera Can Ruti S-N, Badalona 08916, Spain

来源：

JOURNAL OF CARDIOVASCULAR NURSING | 2016年 / 31卷 / 02期

关键词：

type 2 diabetes mellitus; carotid intima-media thickness; primary prevention; atherosclerotic plaque; cardiovascular diseases; INTIMA-MEDIA THICKNESS; CARDIOVASCULAR RISK-FACTORS; ISCHEMIC-STROKE; DISEASE; POPULATION; MORTALITY; SMOKING; PLAQUE; MICROANGIOPATHY; COMPLICATIONS;

D O I：

10.1097/JCN.0000000000000236

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Subjects with type 2 diabetes mellitus are considered to be at high risk for cardiovascular disease. The identification of carotid atherosclerosis is a validated surrogate marker of cardiovascular disease. Nurses are key professionals in the improvement and intensification of cardiovascular preventive strategies. Aims: The aim is to study the presence of carotid atherosclerosis in a group of asymptomatic subjects with type 2 diabetes mellitus and no previous clinical cardiovascular disease. Methods: A total of 187 patients with type 2 diabetes mellitus and 187 age- and sex-matched subjects without type 2 diabetes mellitus were studied in this cross-sectional, observational, cohort study. Standard operational procedures were applied by the nursing team regarding physical examination and carotid ultrasound assessment. Common, bulb, and internal carotid arteries were explored by measuring intima-media thickness and identifying atherosclerotic plaques. Results: Carotid intima-media thickness (c-IMT) and carotid plaque prevalence were significantly greater in diabetic subjects than in the control group. Carotid plaques and c-IMT were more frequent in men than in women and increased with increasing age. In the multivariate analysis, age, gender, waist circumference, systolic blood pressure, and hypercholesterolemia were positively associated with c-IMT, whereas age, gender, and weight were positively associated with carotid plaque. Conclusion: The current nurse-led study shows that subjects with type 2 diabetes mellitus have a high prevalence of subclinical atherosclerosis that is associated with cardiovascular risk factors.

引用

页码：E1 / E7

页数：7

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