Lumbar puncture and dural sinus thrombosis - A causal or casual association?

被引:69
作者
Canhao, P [1 ]
Batista, P [1 ]
Falcao, F [1 ]
机构
[1] Hosp Santa Maria, Dept Neurol, Serv Neurol, PT-1649035 Lisbon, Portugal
关键词
lumbar puncture; dural sinus thrombosis; venous blood flow; transcranial Doppler;
D O I
10.1159/000081912
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: A few cases of cerebral venous thrombosis (CVT) were reported after a lumbar puncture (LP), suggesting a causal association. The purpose of our study was to document that LP might predispose to CVT by decreasing blood flow velocities (BFV) in veins or dural sinus. Methods: We performed a transcranial Doppler ultrasound study to register the mean BFV of the straight sinus ( SS) before, during and after LP. Results: Thirteen patients were studied. LP induced a decrease of 47% of mean BFV in the SS. The mean decrease of BFV was significant immediately at the end (p = 0.003), 30 min after (p = 0.015) and more than 6 h after LP (p = 0.008). Conclusions: LP induced a sustained decrease of mean BFV in the SS. The decrease of venous blood flow is a possible mechanism contributing to the occurrence of CVT. Copyright (C) 2005 S. Karger AG, Basel.
引用
收藏
页码:53 / 56
页数:4
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