Metallodendrimers as transphosphorylation catalysts

被引:60
作者
Martin, Marco
Manea, Flavio
Fiammengo, Roberto
Prins, Leonard J.
Pasquato, Lucia
Scrimin, Paolo [1 ]
机构
[1] Univ Padua, Dept Chem Sci, I-35131 Padua, Italy
[2] Univ Padua, ITM, CNR, Padova Sect, I-35131 Padua, Italy
[3] Univ Trieste, Dept Chem Sci, I-34127 Trieste, Italy
关键词
D O I
10.1021/ja070980o
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The Zn-II complexes of triazacyclononane-functionalized DAB dendrimers are powerful catalysts for the cleavage of an RNA model substrate with clear evidence of cooperativity between two metal centers.
引用
收藏
页码:6982 / +
页数:3
相关论文
共 27 条
[1]   Dendritic catalysts and dendrimers in catalysis [J].
Astruc, D ;
Chardac, F .
CHEMICAL REVIEWS, 2001, 101 (09) :2991-3023
[2]   About dendrimers: Structure, physical properties, and applications [J].
Bosman, AW ;
Janssen, HM ;
Meijer, EW .
CHEMICAL REVIEWS, 1999, 99 (07) :1665-1688
[3]   Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents [J].
Darbre, Tamis ;
Reymond, Jean-Louis .
ACCOUNTS OF CHEMICAL RESEARCH, 2006, 39 (12) :925-934
[4]   POLY(PROPYLENE IMINE) DENDRIMERS - LARGE-SCALE SYNTHESIS BY HETEREOGENEOUSLY CATALYZED HYDROGENATIONS [J].
DEBRABANDERVANDENBERG, EMM ;
MEIJER, EW .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (09) :1308-1311
[5]  
DEIORT E, 2004, J AM CHEM SOC, V126, P15642
[6]  
DEIORT E, 2006, J ORG CHEM, V71, P4468
[7]   Selective catalysis with peptide dendrimers [J].
Douat-Casassus, C ;
Darbre, T ;
Reymond, JL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (25) :7817-7826
[8]   Dendrimeric organochalcogen catalysts for the activation of hydrogen peroxide: Improved catalytic activity through statistical effects and cooperativity in successive generations [J].
Francavilla, C ;
Drake, MD ;
Bright, FV ;
Detty, MR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (01) :57-67
[9]   Toward the development of metal-based synthetic nucleases and peptidases: a rationale and progress report in applying the principles of coordination chemistry [J].
Hegg, EL ;
Burstyn, JN .
COORDINATION CHEMISTRY REVIEWS, 1998, 173 :133-165
[10]   On the magnitude and specificity of medium effects in enzyme-like catalysts for proton transfer [J].
Hollfelder, F ;
Kirby, AJ ;
Tawfik, DS .
JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (17) :5866-5874