The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide

被引：547

作者：

Nordmann, P. ^{[1
,2
,3
]}

Poirel, L. ^{[1
,3
]}

机构：

[1] Univ Fribourg, Dept Med, Med & Mol Microbiol Unit, Fac Sci, CH-1700 Fribourg, Switzerland

[2] Hop Cantonal Fribourg, Hop Fribourgeois, Fribourg, Switzerland

[3] South Paris Med Sch, INSERM, U914, K Bicetre, France

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2014年 / 20卷 / 09期

关键词：

Carbapenemase; Enterobacteriaceae; KPC; NDM; OXA-48; METALLO-BETA-LACTAMASE; NDM-1-PRODUCING KLEBSIELLA-PNEUMONIAE; OXACILLINASE-MEDIATED RESISTANCE; CLOACAE CLINICAL ISOLATE; PSEUDOMONAS-AERUGINOSA; ESCHERICHIA-COLI; MOLECULAR CHARACTERIZATION; OXA-48; CARBAPENEMASE; NOSOCOMIAL OUTBREAK; BIOCHEMICAL-CHARACTERIZATION;

D O I：

10.1111/1469-0691.12719

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The spread of carbapenemase producers in Enterobacteriaceae has now been identified worldwide. Three main carbapenemases have been reported; they belong to three classes of -lactamases, which are KPC, NDM, and OXA-48. The main reservoirs of KPC are Klebsiella pneumoniae in the USA, Israel, Greece, and Italy, those of NDM are K.pneumoniae and Escherichia coli in the Indian subcontinent, and those of OXA-48 are K.pneumoniae and Escherichia coli in North Africa and Turkey. KPC producers have been mostly identified among nosocomial isolates, whereas NDM and OXA-48 producers are both nosocomial and community-acquired pathogens. Control of their spread is still possible in hospital settings, and relies on the use of rapid diagnostic techniques and the strict implemention of hygiene measures.

引用

页码：821 / 830

页数：10

共 137 条

[1] OXA-163-Producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010 [J].

Abdelaziz, Mohammed O. ;

Bonura, Celestino ;

Aleo, Aurora ;

El-Domany, Ramadan A. ;

Fasciana, Teresa ;

Mammina, Caterina .

JOURNAL OF CLINICAL MICROBIOLOGY, 2012, 50 (07) :2489-2491

[2] Introduction of OXA-48-producing Enterobacteriaceae to Israeli hospitals by medical tourism [J].

Adler, Amos ;

Shklyar, Maya ;

Schwaber, Mitchell J. ;

Navon-Venezia, Shiri ;

Dhaher, Yacoub ;

Edgar, Rotem ;

Solter, Ester ;

Benenson, Shmuel ;

Masarwa, Samira ;

Carmeli, Yehuda .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (12) :2763-2766

[3] First description of OXA-48-producing Escherichia coli and the pandemic clone ST131 from patients hospitalised at a military hospital in Algeria [J].

Agabou, A. ;

Pantel, A. ;

Ouchenane, Z. ;

Lezzar, N. ;

Khemissi, S. ;

Satta, D. ;

Sotto, A. ;

Lavigne, J. -P. .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2014, 33 (09) :1641-1646

[4] Carbapenem-hydrolyzing oxacillinase, OXA-48, persists in Klebsiella pneumoniae in Istanbul, Turkey [J].

Aktas, Zerrin ;

Kayacan, Cigdem Bal ;

Schneider, Ines ;

Can, Baris ;

Midilli, Kenan ;

Bauernfeind, Adolf .

CHEMOTHERAPY, 2008, 54 (02) :101-106

[5] Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital [J].

Al-Agamy, Mohamed H. ;

Shibl, Atef M. ;

Elkhizzi, Noura A. ;

Meunier, Daniele ;

Turton, Jane F. ;

Livermore, David M. .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2013, 76 (02) :214-216

[6] A STANDARD NUMBERING SCHEME FOR THE CLASS-A BETA-LACTAMASES [J].

AMBLER, RP ;

COULSON, AFW ;

FRERE, JM ;

GHUYSEN, JM ;

JORIS, B ;

FORSMAN, M ;

LEVESQUE, RC ;

TIRABY, G ;

WALEY, SG .

BIOCHEMICAL JOURNAL, 1991, 276 :269-270

[7] Carbapenemase-producing Enterobacteriaceae, US rivers [J].

Aubron, C ;

Poirel, L ;

Ash, RJ ;

Nordmann, P .

EMERGING INFECTIOUS DISEASES, 2005, 11 (02) :260-264

[8] Molecular Characteristics of KPC-Producing Enterobacteriaceae at the Early Stage of Their Dissemination in Poland, 2008-2009 [J].

Baraniak, Anna ;

Grabowska, Anna ;

Izdebski, Radoslaw ;

Fiett, Janusz ;

Herda, Malgorzata ;

Bojarska, Katarzyna ;

Zabicka, Dorota ;

Kania-Pudlo, Marta ;

Mlynarczyk, Grazyna ;

Zak-Pulawska, Zofia ;

Hryniewicz, Waleria ;

Gniadkowski, Marek .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, 55 (12) :5493-5499

[9] GES-18, a New Carbapenem-Hydrolyzing GES-Type β-Lactamasefrom Pseudomonas aeruginosa That Contains Ile80 and Ser170 Residues [J].

Bebrone, Carine ;

Bogaerts, Pierre ;

Delbrueck, Heinrich ;

Bennink, Sandra ;

Kupper, Michael B. ;

de Castro, Roberta Rezende ;

Glupczynski, Youri ;

Hoffmann, Kurt M. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (01) :396-401

[10]

Bejuk Danijela, 2013, Lijec Vjesn, V135, P316

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