How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis?

被引：22

作者：

Rahbar, Habib ^{[1
]}

McDonald, Elizabeth S. ^{[2
]}

Lee, Janie M. ^{[1
,4
]}

Partridge, Savannah C. ^{[1
]}

Lee, Christoph I. ^{[1
,3
,4
]}

机构：

[1] Univ Washington, Sch Med, Dept Radiol, 825 Eastlake Ave East,G3-200, Seattle, WA 98109 USA

[2] Univ Penn, Dept Radiol, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Univ Washington, Sch Publ Hlth, Dept Hlth Serv, Seattle, WA 98109 USA

[4] Hutchinson Inst Canc Outcomes Res, Seattle, WA 98109 USA

来源：

ACADEMIC RADIOLOGY | 2016年 / 23卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Overdiagnosis; breast cancer; breast imaging; screening risks; CARCINOMA IN-SITU; CONTRAST-ENHANCED MRI; LOCAL RECURRENCE; SCREENING MAMMOGRAPHY; RISK; DIAGNOSIS; WOMEN; EXPRESSION; DIFFUSION; GRADE;

D O I：

10.1016/j.acra.2016.02.008

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Radiologists, as administrators and interpreters of screening mammography, are considered by some to be major contributors to the potential harms of screening, including overdiagnosis and overtreatment. In this article, we outline current efforts within the breast imaging community toward mitigating screening harms, including the widespread adoption of tomosynthesis and potentially adjusting screening frequency and thresholds for image-guided breast biopsy. However, the emerging field of breast radiomics may offer the greatest promise for reducing overdiagnosis by identifying imaging-based biomarkers strongly associated with tumor biology, and therefore helping prevent the harms of unnecessary treatment for indolent cancers.

引用

页码：768 / 773

页数：6

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