Stem Cell Therapy for Spinal Cord Injury: A Review of Recent Clinical Trials

被引：12
作者：
Damianakis, Emmanouil I. [1 ]
Benetos, Ioannis S. [2 ]
Evangelopoulos, Dimitrios Stergios [2 ]
Kotroni, Aikaterini [1 ]
Vlamis, John [2 ]
Pneumaticos, Spyridon G. [2 ]
机构：
[1] KAT Hosp, Phys Med & Rehabil, Athens, Greece
[2] Natl & Kapodistrian Univ Athens NKUA, KAT Hosp, Sch Med, Dept Orthopaed Surg 3, Athens, Greece
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 04期
关键词：
paraplegia; tetraplegia; functional recovery; clinical trial; stem cells; cell therapy; spinal cord injury; REPEATED SUBARACHNOID ADMINISTRATIONS; MYELIN-ASSOCIATED GLYCOPROTEIN; MESENCHYMAL STROMAL CELLS; TRANSPLANTATION; INHIBITOR; DIFFERENTIATION;
D O I：
10.7759/cureus.24575
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Spinal cord injury (SCI) remains an incurable, life-changing neurological condition, causing permanent loss of motor and sensory function in millions of people worldwide and affecting them in every aspect of their personal and social life. In the last two decades, after its success in various fields of medicine, stem cell therapy has been investigated in the research field as a potential treatment for SCI. This review focuses on the pathophysiology of SCI, the characteristics of the different stem cell therapies used for its treatment, and the results of these therapies in published clinical trials.
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页数：10
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