Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study

被引：17
|
作者：
Salazar-Vizcaya, Luisa [1 ]
Wandeler, Gilles [1 ,9 ,10 ]
Fehr, Jan [2 ]
Braun, Dominique [2 ,3 ,4 ]
Cavassini, Matthias [3 ,4 ]
Stoeckle, Marcel [5 ]
Bernasconi, Enos [6 ]
Hoffmann, Matthias [7 ]
Rougemont, Mathieu [8 ]
Beguelin, Charles [1 ]
Rauch, Andri [1 ]
机构：
[1] Univ Bern, Bern Univ Hosp, Dept Infect Dis, Bern, Switzerland
[2] Univ Hosp Zurich, Div Infect Dis & Hosp Epidemiol, Zurich, Switzerland
[3] Univ Zurich, Inst Med Virol, Zurich, Switzerland
[4] Univ Lausanne, Univ Hosp Lausanne, Div Infect Dis, Lausanne, Switzerland
[5] Univ Hosp Basel, Dept Infect Dis & Hosp Hyg, Basel, Switzerland
[6] Reg Hosp Lugano, Div Infect Dis, Lugano, Switzerland
[7] Cantonal Hosp St Gallen, Div Infect Dis & Hosp Epidemiol, St Gallen, Switzerland
[8] Univ Geneva, Univ Hosp Geneva, Div Infect Dis, Geneva, Switzerland
[9] Univ Bern, Inst Social & Prevent Med, Bern, Switzerland
[10] Univ Zurich, Epidemiol Biostat & Prevent Inst, Dept Publ Hlth, Zurich, Switzerland
来源：
OPEN FORUM INFECTIOUS DISEASES | 2018年 / 5卷 / 07期
基金：
瑞士国家科学基金会;
关键词：
DAA; HCV; viral replication; PWID; MSM; HEPATITIS-C VIRUS; POSITIVE MEN; TRANSMISSION; REINFECTION; COINFECTION; SURVIVAL; PEOPLE;
D O I：
10.1093/ofid/ofy154
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In the Swiss HIV Cohort Study, the number of people who inject drugs with replicating hepatitis C virus (HCV) infection decreased substantially after the introduction of direct-acting antivirals (DAAs). Among men who have sex with men, the increase in DAA uptake and efficacy was counterbalanced by frequent incident HCV infections.
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页数：4
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