Species distribution, virulence factors and antimicrobial resistance of Acinetobacter spp. isolates from dogs and cats: a preliminary study

被引：17
作者：
Kimura, Yui [1 ,2 ]
Harada, Kazuki [1 ,3 ]
Shimizu, Takae [1 ,3 ]
Sato, Tomomi [4 ]
Kajino, Akari [4 ]
Usui, Masaru [4 ]
Tamura, Yutaka [4 ]
Tsuyuki, Yuzo [5 ]
Miyamoto, Tadashi [2 ]
Ohki, Asami [6 ]
Watarai, Masahisa [1 ]
机构：
[1] Yamaguchi Univ, United Grad Sch Vet Sci, 1677-1 Yoshida, Yamaguchi 7538515, Japan
[2] Miyamoto Anim Hosp, 2265-8 Kurokawa, Yamaguchi 7530851, Japan
[3] Tottori Univ, Dept Vet Internal Med, Minami 4-101, Koyama, Tottori 6808553, Japan
[4] Rakuno Gakuen Univ, Lab Food Microbiol & Food Safety, 582 Midori, Ebetsu, Hokkaido 0698501, Japan
[5] Sanritsu Zelkova Vet Lab, Takatsu Ku, 2-5-8 Kuji, Kawasaki, Kanagawa 2130032, Japan
[6] Fujifilm Monoris, 1-49-18 Nishikoigakubo, Kokubunji, Tokyo 1850013, Japan
来源：
MICROBIOLOGY AND IMMUNOLOGY | 2018年 / 62卷 / 07期
关键词：
Acinetobacter spp; antimicrobial resistance; virulence factor; COMPANION ANIMALS; MOLECULAR CHARACTERIZATION; BAUMANNII; GENE; IDENTIFICATION; DETERMINANTS; MUTATIONS; PATHOGEN; GYRA;
D O I：
10.1111/1348-0421.12601
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this study, the prevalence of virulence factors and antimicrobial resistance among 67 Acinetobacter spp. isolates, consisting of 21 Acinetobacter baumannii and 46 non-baumannii Acinetobacter obtained from companion animals, was investigated. PCR analysis showed that the most prevalent virulence gene was afa/draBC (29.9%), followed by papC (22.4%) and cvaC (20.9%). Antimicrobial susceptibility testing revealed that resistance to gentamicin (14.9%) and ciprofloxacin (11.9%) was relatively prevalent. Five gentamicin- and/or ciprofloxacin-resistant A. baumannii strains were assigned to ST25, ST149, ST164, ST203 and ST1198. All ciprofloxacin-resistant isolates harbored point mutations in gyrA and/or parC. To the best of our knowledge, this is the first report of preliminary monitoring of animal-origin Acinetobacter spp. in Japan.
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页码：462 / 466
页数：5
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