In the Modern computers for performing the operation of ALU (Arithmetic Logic Unit) like Addition, Subtraction, different types of adders are using for achieving low delay and fast output. QSD numbers are using for giving the carry-free addition so that ALU operations can perform in low delay and speed of the modern computer can increase. In the modern digital system fast adder, Subtraction can perform by use QSD numbers. The range of QSD numbers is -3 to +3. In this paper, we are performing the 4 Bit QSD Addition and subtraction by Reversible Logic Gate based Full adder. For performing fast operation, we are also introducing Pipelining so that delay can be further reduced in the process of addition and subtraction. As we can see from the results session, the delay get reduce up to 92 % by apply Reversible Logic Gate based full adder with Pipelining.