Substituted tren-capped porphyrins:: probing the influence of copper in synthetic models of cytochrome c oxidase

被引：19

作者：

Didier, A

L'Her, M

Boitrel, B ^{[1
]}

机构：

[1] Univ Rennes 1, Inst Chim, CNRS, UMR 6509, F-35042 Rennes, France

[2] Univ Bretagne Occidentale, Fac Sci, CNRS, UMR 6521, F-29285 Brest, France

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 08期

关键词：

D O I：

10.1039/b300604b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tris(2-aminoethylamine) (tren)-capped porphyrins bearing electron donating or withdrawing groups on the amino functions of their tripod have been synthesised and the catalytic activity of each complex was carefully studied both as the iron and the iron-copper complexes: only one of our iron-copper complexes was shown to be active and selective towards the reduction of dioxygen to water.

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页码：1274 / 1276

页数：3

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共 19 条

[1] Functional analogues of the dioxygen reduction site in cytochrome oxidase:: Mechanistic aspects and possible effects of CuB [J].

Boulatov, R ;

Collman, JP ;

Shiryaeva, IM ;

Sunderland, CJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (40) :11923-11935

[2] Biomimetic studies of terminal oxidases: Trisimidazole picket metalloporphyrins [J].

Collman, JP ;

Sunderland, CJ ;

Boulatov, R .

INORGANIC CHEMISTRY, 2002, 41 (08) :2282-2291

[3] CONGRUENT MULTIPLE MICHAEL ADDITION FOR THE SYNTHESIS OF BIOMIMETIC HEME ANALOGS [J].

COLLMAN, JP ;

ZHANG, XM ;

HERRMANN, PC ;

UFFELMAN, ES ;

BOITREL, B ;

STRAUMANIS, A ;

BRAUMAN, JI .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (06) :2681-2682

[4] A functional model related to cytochrome c oxidase and its electrocatalytic four-electron reduction of O-2 [J].

Collman, JP ;

Fu, L ;

Herrmann, PC ;

Zhang, XM .

SCIENCE, 1997, 275 (5302) :949-951

[5] Functional analogs of heme protein active sites [J].

Collman, JP .

INORGANIC CHEMISTRY, 1997, 36 (23) :5145-5155

[6] Mass spectrometric determination of dioxygen bond splitting in the "peroxy" intermediate of cytochrome c oxidase [J].

Fabian, M ;

Wong, WW ;

Gennis, RB ;

Palmer, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (23) :13114-13117

[7] Heme/copper terminal oxidases [J].

FergusonMiller, S ;

Babcock, GT .

CHEMICAL REVIEWS, 1996, 96 (07) :2889-2907

[8] (F8TPP)FeII/O2 reactivity studies {F8TPP = tetrakis(2,6-difluorophenyl)porphyrinate(2-)}:: Spectroscopic (UV-visible and NMR) and kinetic study of solvent-dependent (Fe/O2=1:1 or 2:1) reversible O2-reduction and ferryl formation [J].

Ghiladi, RA ;

Kretzer, RM ;

Guzei, I ;

Rheingold, AL ;

Neuhold, YM ;

Hatwell, KR ;

Zuberbühler, AD ;

Karlin, KD .

INORGANIC CHEMISTRY, 2001, 40 (23) :5754-5767

[9] Dioxygen reactivity of reduced heme and heme-copper complexes utilizing tetraarylporphyrinates tethered with both a pyridyl axial ligand and N,N-bis[2-(2-pyridyl)ethyl]amine chelate [J].

Kopf, MA ;

Karlin, KD .

INORGANIC CHEMISTRY, 1999, 38 (22) :4922-4923

[10] Heme-Cu complexes as oxygen-activating functional models for the active site of cytochrome c oxidase [J].

Naruta, Y ;

Sasaki, T ;

Tani, F ;

Tachi, Y ;

Kawato, N ;

Nakamura, N .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2001, 83 (04) :239-246