Termination of drug-induced torsades de pointes with overdrive pacing

被引：16

作者：

Charlton, Nathan P. ^{[1
]}

Lawrence, David T. ^{[1
]}

Brady, William J. ^{[1
]}

Kirk, Mark A. ^{[1
]}

Holstege, Christopher P. ^{[1
]}

机构：

[1] Univ Virginia, Sch Med, Div Med Toxicol, Dept Emergency Med, Charlottesville, VA 22908 USA

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2010年 / 28卷 / 01期

关键词：

INDUCED QT-PROLONGATION; MECHANISM;

D O I：

10.1016/j.ajem.2008.09.029

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Drug-induced prolongation of the QT interval is frequently encountered after medication overdose. Such toxicity can result in degeneration to torsades de pointes (TdP) and require overdrive pacing. We present 3 cases in which intentional medication overdose resulted in QTc prolongation with subsequent degeneration to TdP. Despite appropriate care, including magnesium therapy, each case required overdrive pacing for resolution of TdP. Although rarely encountered, patients with drug-induced TdP can be successfully managed with overdrive pacing. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：95 / 102

页数：8

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