A structured programme to withdraw antipsychotics among adults with intellectual disabilities: The Cornwall experience

被引:28
作者
Shankar, Rohit [1 ,2 ]
Wilcock, Mike [3 ]
Deb, Shoumitro [4 ]
Goodey, Rebecca [1 ]
Corson, Eve [1 ]
Pretorius, Charlotte [1 ]
Praed, Georgina [3 ]
Pell, Amanda [3 ]
Vujkovic, Dee [1 ]
Wilkinson, Ellen [1 ]
Laugharne, Richard [1 ]
Axby, Sharon [1 ]
Sheehan, Rory [5 ]
Alexander, Regi [6 ]
机构
[1] Cornwall Partnership NHS Fdn Trust, Truro, England
[2] Univ Exeter, Med Sch, Exeter, Devon, England
[3] Kernow Clin Commissioning Grp, St Austell, England
[4] Imperial Coll London, London, England
[5] UCL, London, England
[6] Univ Leicester, Leicester, Leics, England
关键词
adults; antipsychotics withdrawal; challenging behaviour; intellectual disabilities; structured pathway; AGGRESSIVE CHALLENGING BEHAVIOR; PSYCHOTROPIC MEDICATION USE; DRUG USE; PEOPLE; DISCONTINUATION; INDIVIDUALS; PREVALENCE; REDUCTION; SETTINGS; SYMPTOMS;
D O I
10.1111/jar.12635
中图分类号
G44 [教育心理学];
学科分类号
0402 ; 040202 ;
摘要
Background Antipsychotic medications are used among 19%-58% of adults with intellectual disabilities to manage challenging behaviour against the NICE guideline recommendations. Studies show that it is possible to completely withdraw antipsychotics in about one third of adults with intellectual disabilities and a dose reduction of 50% or more in another third. Method In Cornwall, over three years the present authors developed a structured pathway to withdraw antipsychotics among adults with intellectual disabilities which involved people with intellectual disabilities and their carers, GPs, community learning disability team members and pharmacists. Results The present authors managed to withdraw antipsychotics totally among 46.5% (33/71) and reduced over 50% of dosage in another 11.3% (8/71) of adults with intellectual disabilities. At three months follow-up no one required hospital admission or change in placement. Conclusion It is possible to withdraw/reduce antipsychotics in a high proportion of adults with intellectual disabilities if a concerted effort is made involving all stakeholders from the outset.
引用
收藏
页码:1389 / 1400
页数:12
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