Wound healing after laser skin resurfacing: The effect of a silver sulfadiazine-hyaluronic acid-containing cream under an occlusive dressing

被引：5

作者：

Kontoes, Paraskevas P. ^{[1
]}

Vrettou, Charis P. ^{[1
]}

Loupatatzi, Anastasia N. ^{[1
]}

Marayiannis, Konstantinos V. ^{[1
]}

Foukas, Periklis G. ^{[2
]}

Vlachos, Spiros P. ^{[1
]}

机构：

[1] Laserlight Clin, Athens, Greece

[2] Locus Medicus Labs, Athens, Greece

来源：

JOURNAL OF COSMETIC AND LASER THERAPY | 2010年 / 12卷 / 01期

关键词：

Hyaluronic acid; laser skin resurfacing; silver sulfadiazine; wound healing; CARE;

D O I：

10.3109/14764170903449752

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Introduction: Occlusive dressings promote wound healing after laser skin resurfacing. Our goal was to evaluate whether a cream containing hyaluronic acid-silver sulfadiazine could improve this process. Methods: Ten guinea pigs received laser resurfacing on the skin of their backs. Polyurethane foam film adhesive dressing was applied. A cream containing hyaluronic acid-silver sulfadiazine was applied under the dressing over half of the wound. Skin biopsies were taken at days 2, 4, 7 and 9 and examined by a pathologist blinded to the study. Results: Re-epithelialization appeared to occur faster in the cream-treated areas, together with a lower level of acute inflammation in the early phase of the healing process. Conclusions: The cream containing silver sulfadiazine/hyaluronic acid seems to improve wound healing after laser skin resurfacing in guinea pigs. The clinical application of this finding on humans should be assessed.

引用

页码：10 / 13

页数：4

共 10 条

[1] Prevention and treatment of side effects and complications of cutaneous laser resurfacing [J].