p-Adic hierarchical properties of the genetic code

被引:16
作者
Dragovich, Branko [1 ,2 ]
Misic, Natasa Z. [3 ]
机构
[1] Univ Belgrade, Inst Phys, Belgrade, Serbia
[2] Serbian Acad Arts & Sci, Math Inst, Belgrade, Serbia
[3] Lola Ltd, Res & Dev Inst, Kneza Viseslava 70a, Belgrade, Serbia
关键词
Genetic code; p-Adic distance; Ultrametric codon tree; Amino acids; Genetic language; p-Adic network; Bioinformation; CANONICAL AMINO-ACIDS; EVOLUTION; MODEL; SYSTEMATIZATION; ORIGIN;
D O I
10.1016/j.biosystems.2019.104017
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this article, we consider p-adic modeling of the standard genetic code and the vertebrate mitochondrial one. To this end, we use 5-adic and 2-adic distance as a mathematical tool to describe closeness (nearness, similarity) between codons as elements of a bioinformation space. Codons which are simultaneously at the smallest 5-adic and 2-adic distance code the same (or similar) amino acid or stop signal. The set of codons is presented as an ultrametric tree as well as a fractal and p-adic network. It is shown that genetic code can be treated as sequential translation between genetic languages. This p-adic approach gives possibility to be applied to sequences of nucleotides of an arbitrary finite length. We present an overview of published and some new results on various p-adic properties of the genetic code.
引用
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页数:12
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