Review of Diagnostic Biomarkers in Autoimmune Pancreatitis: Where Are We Now?

被引：12
作者：
Yokode, Masataka [1 ]
Shiokawa, Masahiro [1 ]
Kodama, Yuzo [2 ]
机构：
[1] Kyoto Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, Kyoto 6068507, Japan
[2] Kobe Univ, Div Gastroenterol, Dept Internal Med, Grad Sch Med, Kobe, Hyogo 6500017, Japan
来源：
DIAGNOSTICS | 2021年 / 11卷 / 05期
基金：
日本学术振兴会;
关键词：
autoimmune pancreatitis; IgG4-related disease; autoantibody; biomarker; diagnosis; SECRETORY TRYPSIN-INHIBITOR; IDIOPATHIC CHRONIC-PANCREATITIS; LONG NONCODING RNAS; CARBONIC-ANHYDRASE; SERUM IGG4; IFN-ALPHA; IDENTIFICATION; ANTIBODIES; AUTOTAXIN; SEQUENCE;
D O I：
10.3390/diagnostics11050770
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Autoimmune pancreatitis (AIP) is a pancreatic manifestation of an IgG4-related disease (IgG4-RD). AIP lacks disease-specific biomarkers, and therefore, it is difficult to distinguish AIP from malignancies, especially pancreatic cancer. In this review, we have summarized the latest findings on potential diagnostic biomarkers for AIP. Many investigations have been conducted, but no specific biomarkers for AIP are identified. Therefore, further studies are required to identify accurate diagnostic biomarkers for AIP.
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页数：11
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