Combination of romiplostim and rituximab: effective therapy of severe immune thrombocytopenia

被引:9
作者
Pohlen, Michele [1 ]
Sargin, Buelent [1 ]
Zicholl, Stefan [1 ]
Bisping, Guido [1 ]
Mueller-Tidow, Carsten [1 ]
Berdel, Wolfgang E. [1 ]
Mesters, Rolf [1 ]
Koschmieder, Steffen [1 ]
机构
[1] Univ Munster, Dept Med Hematol & Oncol, D-48149 Munster, Germany
关键词
CONTROLLED-TRIAL; DOUBLE-BLIND; CHRONIC ITP; PURPURA; EFFICACY; ADULTS; SAFETY;
D O I
10.1111/j.1600-0609.2009.01406.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:362 / 364
页数:3
相关论文
共 8 条
[1]   MECHANISMS OF THROMBOCYTOPENIA IN CHRONIC AUTOIMMUNE THROMBOCYTOPENIC PURPURA - EVIDENCE OF BOTH IMPAIRED PLATELET PRODUCTION AND INCREASED PLATELET CLEARANCE [J].
BALLEM, PJ ;
SEGAL, GM ;
STRATTON, JR ;
GERNSHEIMER, T ;
ADAMSON, JW ;
SLICHTER, SJ .
JOURNAL OF CLINICAL INVESTIGATION, 1987, 80 (01) :33-40
[2]   Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP) [J].
Boruchov, Donna M. ;
Gururangan, Sri ;
Driscoll, M. Catherine ;
Bussel, James B. .
BLOOD, 2007, 110 (10) :3526-3531
[3]   AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP [J].
Bussel, James B. ;
Kuter, David J. ;
George, James N. ;
McMillan, Robert ;
Aledort, Louis M. ;
Conklin, George T. ;
Lichtin, Alan E. ;
Lyons, Roger M. ;
Nieva, Jorge ;
Wasser, Jeffrey S. ;
Wiznitzer, Israel ;
Kelly, Reggie ;
Chen, Chien-Feng ;
Nichol, Janet L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (16) :1672-1681
[4]   Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial [J].
Bussel, James B. ;
Provan, Drew ;
Shamsi, Tahir ;
Cheng, Gregory ;
Psaila, Bethan ;
Kovaleva, Lidia ;
Salama, Abdulgabar ;
Jenkins, Julian M. ;
Roychowdhury, Debasish ;
Mayer, Bhabita ;
Stone, Nicole ;
Arning, Michael .
LANCET, 2009, 373 (9664) :641-648
[5]   Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP [J].
Bussel, James B. ;
Kuter, David J. ;
Pullarkat, Vinod ;
Lyons, Roger M. ;
Guo, Matthew ;
Nichol, Janet L. .
BLOOD, 2009, 113 (10) :2161-2171
[6]   The efficacy and safety of B-cell depletion with anti-CD20 monoclonal antibody in adults with chronic immune thrombocytopenic purpura [J].
Cooper, N ;
Stasi, R ;
Cunningham-Rundles, SS ;
Feuerstein, MA ;
Leonard, JP ;
Amadori, S ;
Bussel, JB .
BRITISH JOURNAL OF HAEMATOLOGY, 2004, 125 (02) :232-239
[7]   Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura:: a double-blind randomised controlled trial [J].
Kuter, David J. ;
Bussel, James B. ;
Lyons, Roger M. ;
Pullarkat, Vinod ;
Gernsheimer, Terry B. ;
Senecal, Francis M. ;
Aledort, Louis M. ;
George, James N. ;
Kessler, Craig M. ;
Sanz, Miguel A. ;
Liebman, Howard A. ;
Slovick, Frank T. ;
de Wolf, J. Th M. ;
Bourgeois, Emmanuelle ;
Guthrie, Troy H., Jr. ;
Newland, Adrian ;
Wasser, Jeffrey S. ;
Hamburg, Solomon I. ;
Grande, Carlos ;
Lefrere, Francois ;
Lichtin, Alan Eli ;
Tarantino, Michael D. ;
Terebelo, Howard R. ;
Viallard, Jean-Francois ;
Cuevas, Francis J. ;
Go, Ronald S. ;
Henry, David H. ;
Redner, Robert L. ;
Rice, Lawrence ;
Schipperus, Martin R. ;
Guo, D. Matthew ;
Nichol, Janet L. .
LANCET, 2008, 371 (9610) :395-403
[8]   Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group [J].
Rodeghiero, Francesco ;
Stasi, Roberto ;
Gernsheimer, Terry ;
Michel, Marc ;
Provan, Drew ;
Arnold, Donald M. ;
Bussel, James B. ;
Cines, Douglas B. ;
Chong, Beng H. ;
Cooper, Nichola ;
Godeau, Bertrand ;
Lechner, Klaus ;
Mazzucconi, Maria Gabriella ;
McMillan, Robert ;
Sanz, Miguel A. ;
Imbach, Paul ;
Blanchette, Victor ;
Kuehne, Thomas ;
Ruggeri, Marco ;
George, James N. .
BLOOD, 2009, 113 (11) :2386-2393