Novel monitoring strategies for xenoestrogens

The wide variety of known and unknown xenoestrogenic compounds requires intelligent solutions to detect polluted environmental samples and identify the structure and concentration of the relevant xenoestrogens. In this article, a summary is given of several methods that are at present employed in the monitoring of xenoestrogens, Screening methods based on biological assays for the class-selective detection of xenoestrogens are reviewed, Furthermore, the analysis of known (xeno-)estrogens is summarized. Novel interfaces between biological assays and chromatography that facilitate the identification and quantification of xenoestrogens in complex samples are also discussed. (C) 1997 Elsevier Science B.V.