Prominent effect of platelet on improvement of liver cirrhosis

被引：2

作者：

Xu, Hui ^{[1
,2
]}

Jiang, Xiao-Meng ^{[3
,4
]}

Wu, Ying ^{[3
]}

Li, Yu-Mei ^{[1
,2
]}

Zheng, Yun-Wen ^{[1
,5
,6
,7
]}

Ohkohchi, Nobuhiro ^{[6
]}

机构：

[1] Jiangsu Univ, Affiliated Hosp, Inst Regenerat Med, Zhenjiang 212001, Jiangsu, Peoples R China

[2] Jiangsu Univ, Affiliated Hosp, Dept Dermatol, Zhenjiang 212001, Jiangsu, Peoples R China

[3] Jiangsu Univ, Affiliated Hosp, Dept Gastroenterol, Zhenjiang 212001, Jiangsu, Peoples R China

[4] Nanjing Med Univ, Sir Run Run Hosp, Digest Dept, Nanjing 211166, Peoples R China

[5] Yokohama City Univ, Sch Med, Dept Regenerat Med, Yokohama, Kanagawa, Japan

[6] Univ Tsukuba, Fac Med, Dept Surg, Tsukuba, Ibaraki, Japan

[7] Univ Tokyo, Ctr Stem Cell Biol & Regenerat Med, Inst Med Sci, Div Regenerat Med, Tokyo, Japan

来源：

AME CASE REPORTS | 2020年 / 4卷

关键词：

Liver cirrhosis; platelet; liver function; thrombopoietin (TPO); case report; THROMBOPOIETIN THERAPY; THROMBOCYTOPENIA; TRANSPLANTATION; MANAGEMENT; FIBROSIS; DISEASE;

D O I：

10.21037/acr.2020.04.02

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Thrombopoietin (TPO) can improve liver regeneration and fibrosis. We report on a patient with liver cirrhosis who received treatment with TPO to improve liver function. An 82-year-old male had liver cirrhosis with ascites due to hepatitis C virus infection. The Child-Pugh classification was Child B. The patient received human recombinant TPO for 12 months. The platelet counts increased and were maintained at 60-80x10(9)/L. The liver function improved, the ascites resolved, and the liver volume increased. These results indicate that the novel treatment with recombinant human TPO (rhTPO) may be effective for improving liver function in patients with liver cirrhosis.

引用

页数：4

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