Isolation and Characterization of a Novel Tembusu Virus Circulating in Muscovy Ducks in South China

被引:27
作者
Yan, Z. [1 ,2 ]
Shen, H. [1 ]
Wang, Z. [2 ]
Lin, W. [1 ]
Xie, Q. [1 ]
Bi, Y. [1 ]
Chen, F. [1 ]
机构
[1] South China Agr Univ, Coll Anim Sci, 483 Wushan Rd, Guangzhou 510642, Guangdong, Peoples R China
[2] Guangdong Wens Foodstuff Grp Co Ltd, Guangdong Enterprise Key Lab Anim Hlth & Environm, Yunfu, Peoples R China
关键词
isolation; Tembusu virus; Muscovy duck; phylogenetic analysis; FLAVIVIRUS;
D O I
10.1111/tbed.12525
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Duck Tembusu virus (DTMUV) is an infectious pathogen that can cause epidemics in egg-laying ducks. Here, we isolated and characterized a DTMUV, designated GDLH01, thought to be responsible for the noticeable egg drop in Muscovy duck flocks in South China since 2011. The genome sequence of GDLH01 shared 97-99% homology with other avian-origin Tembusu viruses, and 99.5% homology with the mosquito-borne strain SDMS recently reported in China. Phylogenetic analysis based on the nucleotide sequence of the entire open reading frame confirmed that the isolate was of avian origin and closely related to a mosquito-borne strain. Our findings characterize a novel Tembusu virus circulating in Muscovy ducks in South China and emphasize the importance of reinforcing biosecurity measures and developing vaccines to prevent the spread of this viral pathogen.
引用
收藏
页码:E15 / E17
页数:3
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