Effects of astaxanthin in obese mice fed a high-fat diet

被引:161
作者
Ikeuchi, Mayumi [1 ]
Koyama, Tomoyuki [1 ]
Takahashi, Jiro [1 ]
Yazawa, Kazunaga [1 ]
机构
[1] Tokyo Univ Marine Sci & Technol, Grad Sch Marine Sci & Technol, Lab Nertraceut & Funct Foods Sci, Minato Ku, Tokyo 1088477, Japan
关键词
astaxanthin; high-fat diet; obesity;
D O I
10.1271/bbb.60521
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Astaxanthin is a natural antioxidant carotenoid that occurs in a wide variety of living organisms. We investigated the effects of astaxanthin supplementation in obese,mice fed a high-fat diet. Astaxanthin inhibited the increases in body weight and weight of adipose tissue that result from feeding a high-fat diet. In addition, astaxanthin reduced liver weight, liver triglyceride, plasma triglyceride, and total cholesterol. These results suggest that astaxanthin might be of value in reducing the likelihood of obesity and metabolic syndrome in affluent societies.
引用
收藏
页码:893 / 899
页数:7
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