Emerging Tools for Stroke Prevention in Atrial Fibrillation

被引:12
作者
Voukalis, Christos [1 ]
Lip, Gregory Y. H. [1 ]
Shantsila, Eduard [1 ]
机构
[1] Univ Birmingham, City Hosp, Inst Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
来源
EBIOMEDICINE | 2016年 / 4卷
关键词
Atrial fibrillation; Stroke prevention; Risk stratification; Oral anticoagulation; Non-vitamin K oral anticoagulants; Net clinical benefit; ACUTE ISCHEMIC-STROKE; NET CLINICAL BENEFIT; RISK STRATIFICATION SCHEMES; HEART RHYTHM ASSOCIATION; MOLECULAR-WEIGHT HEPARIN; CARDIOLOGY WORKING GROUP; VITAMIN-K ANTAGONISTS; HAS-BLED SCORE; FIBRIN D-DIMER; ANTITHROMBOTIC THERAPY;
D O I
10.1016/j.ebiom.2016.01.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ischaemic strokes resulting from atrial fibrillation (AF) constitute a devastating condition for patients and their carerswith huge burden on health care systems. Prophylactic treatment against systemic embolization and ischaemic strokes is the cornerstone for the management of AF. Effective stroke prevention requires the use of the vitamin K antagonists or non-vitamin K oral anticoagulants (NOACs). This article summarises the latest developments in the field of stroke prevention in AF and aims to assist physicians with the choice of oral anticoagulant for patients with non-valvular AF with different risk factor profile. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:26 / 39
页数:14
相关论文
共 132 条
  • [1] Atrial fibrillation in chronic dialysis patients in the United states: risk factors for hospitalization and mortality
    Kevin C Abbott
    Fernando C Trespalacios
    Allen J Taylor
    Lawrence Y Agodoa
    [J]. BMC Nephrology, 4 (1)
  • [2] The Impact of Heart Failure and Left Ventricular Dysfunction in Predicting Stroke, Thromboembolism, and Mortality in Atrial Fibrillation Patients: A Systematic Review
    Agarwal, Megha
    Apostolakis, Stavros
    Lane, Deirdre A.
    Lip, Gregory Y. H.
    [J]. CLINICAL THERAPEUTICS, 2014, 36 (09) : 1135 - 1144
  • [3] Estimation of the impact of warfarin's time-in-therapeutic range on stroke and major bleeding rates and its influence on the medical cost avoidance associated with novel oral anticoagulant use-learnings from ARISTOTLE, ROCKET-AF, and RE-LY trials
    Amin, Alpesh
    Deitelzweig, Steve
    Jing, Yonghua
    Makenbaeva, Dinara
    Wiederkehr, Daniel
    Lin, Jay
    Graham, John
    [J]. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2014, 38 (02) : 150 - 159
  • [4] The impact of atherosclerotic vascular disease in predicting a stroke, thromboembolism and mortality in atrial fibrillation patients: a systematic review
    Anandasundaram, B.
    Lane, D. A.
    Apostolakis, S.
    Lip, G. Y. H.
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 (05) : 975 - 987
  • [5] ANDERSON DC, 1992, ANN INTERN MED, V116, P6
  • [6] [Anonymous], N ENGL J MED
  • [7] [Anonymous], 2015, EUR HEART J
  • [8] [Anonymous], 2012, CHEST S
  • [9] [Anonymous], EUR HEART J
  • [10] [Anonymous], DUAL SINGL ANT THER