Pharmacological thromboprophylaxis in gynecology and obstetrics

被引：2
作者：
Scharf, R. E. [1 ,2 ]
Pestka, M. A. [3 ,4 ]
机构：
[1] Univ Dusseldorf, Univ Klinikum Dusseldorf, Inst Hamostaseol Hamotherapie & Transfus Med, D-40225 Dusseldorf, Germany
[2] Univ Dusseldorf, Univ Klinikum, Hemophilia Comprehens Care Ctr, D-40225 Dusseldorf, Germany
[3] Univ Freiburg, Univ Klinikum, Klin Gynakol & Gynakol Onkol, Freiburg, Germany
[4] Univ Freiburg, Univ Klinikum, Klin Geburtshilfe & Perinatol, Freiburg, Germany
来源：
HAMOSTASEOLOGIE | 2014年 / 34卷 / 04期
关键词：
Pharmacological thromboprophylaxis; heparins; recombinant and synthetic anticoagulants; cancer; pregnancy; MOLECULAR-WEIGHT HEPARIN; ED AMERICAN-COLLEGE; VENOUS THROMBOEMBOLISM; ANTITHROMBOTIC THERAPY; PREGNANCY COMPLICATIONS; PREVENTION; THROMBOPHILIA; THROMBOSIS; PREECLAMPSIA; WOMEN;
D O I：
10.5482/HAMO-14-07-0029
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Venous thromboembolism (VTE) is associated with high morbidity and mortality. Therefore, effective methods for safe thromboprophylaxis remain an ongoing challenge in daily clinical practice. This is especially true for pregnant women and patients with gynaecological malignancies. Low-molecular weight heparins continue to be agents of choice for pharmacological thromboprophylaxis postoperatively, in pregnant patients at risk, and during the puerperium. However, these drugs can cause bleeds or heparin-induced thrombocytopenia (type II). Based on recent revisions of corresponding guidelines, this article provides an overview of the current state of pharmacological thromboprophylaxis and discusses prevailing problems and unresolved issues.
引用
收藏
页码：277 / 288
页数：12
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