Effect of copper sulphate on the antioxidant parameters in the rainbow trout fry, Oncorhynchus mykiss

被引:19
|
作者
Yonar, M. E. [1 ]
Ispir, U. [2 ]
Yonar, S. Mise [1 ]
Kirici, M. [3 ]
机构
[1] Firat Univ, Fac Fisheries, TR-23119 Elazig, Turkey
[2] Inonu Univ, Fac Fisheries, Malatya, Turkey
[3] Bingol Univ, Fac Agr, Dept Fisheries, Bingol, Turkey
关键词
Copper sulphate; rainbow trout; oxidative stress; antioxidant system; INDUCED OXIDATIVE STRESS; SALMO-GAIRDNERI RICHARDSON; CYPRINUS-CARPIO; LIPID-PEROXIDATION; SUBLETHAL CONCENTRATIONS; BIOCHEMICAL-CHANGES; CHANNEL CATFISH; ELLAGIC ACID; FISH; EXPOSURE;
D O I
10.14715/cmb/2016.62.6.10
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The aim of this study was to evaluate antioxidant responses of rainbow trout (Oncorhynchus mykiss) exposed to different concentrations of copper sulphate (CuSO4). Fish were exposed to 0 (Group I-control), 5 (Group II), 15 (Group III) and 30 mu g/L (Group IV) concentrations of CuSO4 for 14 days. Liver and gills samples were collected at the end of the experiment, and analysed for their oxidant-antioxidant status, including the malondialdehyde (MDA) level, the catalase (CAT) and glutathione peroxidase (GSH-Px) activities as well as the reduced glutathione (GSH) concentration. Results obtained showed that the levels of MDA increased in tissues of fish. Compared to control, GSH level and GSH-Px and CAT activities were significantly reduced in the fish that were exposed to different concentrations of CuSO4. The result demonstrated that CuSO4 has an oxidative-stress-inducing potential in fish.
引用
收藏
页码:55 / 58
页数:4
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