Home screening for sexually transmitted diseases in high-risk young women: randomised control led trial

被引:62
作者
Cook, Robert L.
Ostergaard, Lars
Hillier, Sharon L.
Murray, Pamela J.
Chang, Chung-Chou H.
Comer, Diane M.
Ness, Roberta B.
机构
[1] Univ Florida, Dept Epidemiol & Biostat & Med, Gainesville, FL 32610 USA
[2] Aarhus Univ Hosp, Dept Infect Dis, DK-8000 Aarhus, Denmark
[3] Univ Pittsburgh, Dept Obstet Gynecol & Reprod Hlth Serv, Pittsburgh, PA USA
[4] Univ Pittsburgh, Dept Pediat, Pittsburgh, PA 15260 USA
[5] Univ Pittsburgh, Dept Biostat, Pittsburgh, PA 15261 USA
[6] Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA
[7] Univ Pittsburgh, Ctr Res Hlth Care, Pittsburgh, PA USA
关键词
D O I
10.1136/sti.2006.023762
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objective: Home screening tests could eliminate several barriers to testing sexually transmitted diseases (STDs). Aim: To determine whether offering repeated home screening tests would increase the rate of testing for chlamydia and gonorrhoea in a high-risk sample of young women. Methods: In this randomised controlled trial, 403 young women (mean age 18.9 years, 70% black) with a recent STD or with STD-related risk factors were enrolled. Participants were recruited from clinics and high-prevalence neighbourhoods and then randomly assigned to receive either a home testing kit or an invitation to attend a medical clinic for testing at 6, 12 and 18 months after enrollment. Over 80% of women were followed for 2 years. The trial is registered with ClinicalTr-iols.gov, number NCT 00177437. Results: Of 197 women in the intervention group, 140 (71%) returned at least one home test and 25 of 249 (10%) home tests were positive. Women who received home screening tests completed significantly more STD tests overall (1.94 vs 1.41 tests per woman-year, p < 0.001) and more STD tests in the absence of symptoms (1.18 vs 0.75 tests per woman-year, p < 0.001). More women in the intervention group completed at least one test when asymptomatic (162 (82.2%) vs 117 (61.350, p < 0.001). The intervention was most effective among women recruited outside medical clinics. There was, no significant difference in the overall rate of STDs detected. Conclusions: Home screening significantly increased the utilisation of chlamydia and gonorrhoea testing in this sample of high-risk young women, and thus represents a feasible strategy to facilitate STD testing in young women.
引用
收藏
页码:286 / 291
页数:6
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