Removal of antibiotics during the anaerobic digestion of pig manure

被引:125
作者
Feng, Lu [1 ]
Casas, Monica Escola [2 ]
Ottosen, Lars Ditlev Morck [1 ]
Moller, Henrik Bjarne [1 ]
Bester, Kai [2 ]
机构
[1] Aarhus Univ, Dept Engn, Blichers Alle 20, DK-8830 Tjele, Denmark
[2] Aarhus Univ, Dept Environm Sci, Frederiksborgvej 399, DK-4000 Roskilde, Denmark
关键词
Macrolide; Sulfonamide; Erythromycin; Thermophilic; Psychrophilic; WASTE-WATER; VETERINARY ANTIBIOTICS; MASS-SPECTROMETRY; ANTIMICROBIAL USE; LIQUID MANURE; SULFONAMIDES; TETRACYCLINES; FERMENTATION; ELIMINATION; FATE;
D O I
10.1016/j.scitotenv.2017.05.280
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Antibiotics are frequently used in animals to treat sickness and prevent infection especially in industrial meat production. Some of the antibiotics cannot be completely metabolized and, as an unavoidable result, are excreted and thus end up in manure which is then spread in the environment. Currently increasing amounts of manure is used in biogas production before spreading the residuals on agricultural fields. In this study, the removal patterns of sulfonamides (sulfadiazine, sulfamethizole, sulfamethoxazole) and macrolides (clarithromycin, erythromycin), as well as trimethoprim, were investigated during the anaerobic digestion of pig manure. Batch kinetic tests were conducted both at thermophilic and psychrophilic condition for 40 days. Some of the antibiotics (clarithromycin, sulfadiazine, sulfamethizole) were persistent in all experiments. Thus, no biodegradation was found for sulfadiazine and sulfamethizole in this study. From the studied compounds, only erythromycin was clearly removed and probably degraded during anaerobic digestion with 99% and 20% removal under thermophilic and psychrophilic condition. The removal of erythromycin was fitted to a single first-order kinetic reaction function, giving reaction rate constant of 0.29 day(-1) and 0.005 day(-1), respectively. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:219 / 225
页数:7
相关论文
共 37 条
[1]   The fate of selected micropollutants in a single-house MBR [J].
Abegglen, Christian ;
Joss, Adriano ;
McArdell, Christa S. ;
Fink, Guido ;
Schluesener, Michael P. ;
Ternes, Thomas A. ;
Siegrist, Hansruedi .
WATER RESEARCH, 2009, 43 (07) :2036-2046
[2]   Assessment of full-scale biological nutrient removal systems upgraded with physico-chemical processes for the removal of emerging pollutants present in wastewaters from Mexico [J].
Baltazar Estrada-Arriaga, Edson ;
Enriqueta Cortes-Munoz, Juana ;
Gonzalez-Herrera, Arturo ;
Guillermo Calderon-Molgora, Cesar ;
de Lourdes Rivera-Huerta, Ma. ;
Ramirez-Camperos, Esperanza ;
Montellano-Palacios, Leticia ;
Lucila Gelover-Santiago, Silvia ;
Perez-Castrejon, Sara ;
Cardoso-Vigueros, Lina ;
Martin-Dominguez, Alejandra ;
Garcia-Sanchez, Liliana .
SCIENCE OF THE TOTAL ENVIRONMENT, 2016, 571 :1172-1182
[3]   Biodegradation of pharmaceuticals in hospital wastewater by a hybrid biofilm and activated sludge system (Hybas) [J].
Casas, Monica Escola ;
Chhetri, Ravi Kumar ;
Ooi, Gordon ;
Hansen, Kamilla M. S. ;
Litty, Klaus ;
Christensson, Magnus ;
Kragelund, Caroline ;
Andersen, Henrik R. ;
Bester, Kai .
SCIENCE OF THE TOTAL ENVIRONMENT, 2015, 530 :383-392
[4]  
Eggleston H. S., 2006, IPCC GUIDELINES NATI
[5]   Removal of sulfonamide antibiotics upon conventional activated sludge and advanced membrane bioreactor treatment [J].
Garcia Galan, Maria Jesus ;
Silvia Diaz-Cruz, M. ;
Barcelo, Damia .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 404 (05) :1505-1515
[6]   Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies [J].
Goebel, Anke ;
McArdell, Christa S. ;
Joss, Adriano ;
Siegrist, Hansruedi ;
Giger, Walter .
SCIENCE OF THE TOTAL ENVIRONMENT, 2007, 372 (2-3) :361-371
[7]   Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry [J].
Haller, MY ;
Müller, SR ;
McArdell, CS ;
Alder, AC ;
Suter, MJF .
JOURNAL OF CHROMATOGRAPHY A, 2002, 952 (1-2) :111-120
[8]   Different behavior of tetracyclines and sulfonamides in sandy soils after repeated fertilization with liquid manure [J].
Hamscher, G ;
Pawelzick, HT ;
Höper, H ;
Nau, H .
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2005, 24 (04) :861-868
[9]   Antibiotics in dust originating from a pig-fattening farm: A new source of health hazard for farmers? [J].
Hamscher, G ;
Pawelzick, HT ;
Sczesny, S ;
Nau, H ;
Hartung, J .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2003, 111 (13) :1590-1594
[10]   Occurrence of antibiotics in the aquatic environment [J].
Hirsch, R ;
Ternes, T ;
Haberer, K ;
Kratz, KL .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :109-118