Comparison of Propofol and Etomidate in Haemodynamic changes at the time of induction of general anesthesia

被引:0
作者
Nazeer, Tahir [1 ]
Tahir, Amna [2 ]
Khan, M. Baqir Ali [3 ]
Din, Saeed Taj [4 ]
Shoaib, Muhammad [5 ]
Asif, Muhammad [6 ]
机构
[1] AzraNaheed Med Coll, Anaesthesia, Lahore, Pakistan
[2] KEMU, Physiol, Lahore, Pakistan
[3] Hameed Latif Hosp, Anaesthetist, Lahore, Pakistan
[4] Azra Naheed Med Coll, Orthoped Surg, Lahore, Pakistan
[5] Azra Naheed Med Coll, Surg, Lahore, Pakistan
[6] Azra Naheed Med Coll, Urol, Lahore, Pakistan
来源
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES | 2021年 / 15卷 / 04期
关键词
Propofol; Etomidate; General Anesthesia; Hemodynamic changes; INDUCED MYOCLONUS; HYPOTENSION;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Unstable hemodynamics at the time of induction of general anesthesia can harm the patient, so stability of hemodynamics matters a lot. Aim: To compare the hemodynamic effects of propofol at the time of induction of general anesthesia with etomidate for choosing the better inducing agent. Methods: 100 patients of ASA class P-1&P-2 status under going elective general anesthesia for surgery were included after informed consent. Patients were divided into two groups A & B by using random number table. Each group comprised of 50 patients. In group A, propofol 2.5mg/kg body weight was given intravenously within 30 sec. In group B, Etomidate 0.3 mg/kg body weight intravenously with in 30 sec was given. Heart rate and blood pressure were recorded at interval of 30 sec for 3 min and after 3 min other drugs were given to patients and surgery allowed. The study design was quasi experimental and sampling techniques was purposive non-probability sampling. Student's t test was used and collected data were analyzed with the SPSS version 10. Results: Significant decrease in hart rate, systolic and diastolic blood pressure was recorded with propofol and minimal hemodynamic changes were recorded with etomidate. Conclusion: Etomidate is a better inducing agent as compared to propofol.
引用
收藏
页码:685 / 687
页数:3
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