Effect of early intervention on 5-year outcome in non-affective psychosis

被引：120
作者：
Gafoor, Rafael
Nitsch, Dorothea [2 ]
McCrone, Paul
Craig, Tom K. J.
Garety, Philippa A.
Power, Paddy
McGuire, Philip [1 ]
机构：
[1] Kings Coll London, Inst Psychiat, London SE5 8AF, England
[2] London Sch Hyg & Trop Med, London WC1, England
来源：
BRITISH JOURNAL OF PSYCHIATRY | 2010年 / 196卷 / 05期
基金：
英国医学研究理事会;
关键词：
COGNITIVELY-ORIENTED PSYCHOTHERAPY; RANDOMIZED MULTICENTER TRIAL; STANDARD TREATMENT; DISORDERS; COMMUNITY; PRISONS; COPE;
D O I：
10.1192/bjp.bp.109.066050
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Background Early specialised care may improve short-term outcome in first-episode non-affective psychosis, but it is unclear if these benefits endure. Aims To assess the long-term effect of early intervention in psychosis. Method Individuals with first-episode psychosis were randomised to specialised care or care as usual (trial number: ISRCTN73679874). Outcome after 5 years was assessed by case-note review. Results There were no significant differences in the admission rate (coefficient 0.096, 95% CI -0.550 to 0.742, P=0.770) or the mean number of bed days (coefficient 6.344, 95% CI -46 to 58.7, P= 0.810). Conclusions These findings that specialist intervention did not markedly improved outcome at 5 years accord with those from a larger OPUS study. The sample size of this study was small and these results should be generalised with caution. More research is needed.
引用
收藏
页码：372 / 376
页数：5
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