Pharmacotherapy for Perinatal Depression

被引：13

作者：

Lusskin, Shari I. ^{[1
,2
]}

Khan, Sabrina J. ^{[3
]}

Ernst, Carrie ^{[5
]}

Habib, Sally ^{[3
]}

Fersh, Madeleine E. ^{[4
]}

Albertini, Elizabeth S. ^{[5
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA

[2] Icahn Sch Med Mt Sinai, Dept Obstet Gynecol & Reprod Sci, New York, NY 10029 USA

[3] NYU, Sch Med, Dept Psychiat, New York, NY 10003 USA

[4] Icahn Med Sch Mt Sinai, Dept Psychiat, New York, NY USA

[5] Zucker Sch Med Hofstra Northwell, Dept Psychiat, Hempstead, NY USA

来源：

CLINICAL OBSTETRICS AND GYNECOLOGY | 2018年 / 61卷 / 03期

关键词：

antidepressants; depression; pregnancy; perinatal; breastfeeding; teratogenicity; neonatal complications; neurodevelopment; autism; SEROTONIN-REUPTAKE INHIBITORS; PERSISTENT PULMONARY-HYPERTENSION; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; ANTIDEPRESSANT MEDICATION USE; AUTISM SPECTRUM DISORDER; MATERNAL USE; DISCONTINUATION SYNDROME; PRENATAL EXPOSURE; PREGNANT-WOMEN; PRETERM BIRTH;

D O I：

10.1097/GRF.0000000000000365

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Perinatal depression is associated with serious risks for the mother, baby, and family. When considering treating perinatal depression with a drug indicated for the treatment of depression, the major concerns are whether the drug increases the risks of teratogenicity, pregnancy complications, poor neonatal adaptation, or neurodevelopmental disorders. Although different studies have produced different results, the majority have not shown increases in risk for selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, tricyclic antidepressants, or the noradrenergic/dopaminergic drug bupropion. In this review we will discuss the reproductive safety data for these medications as well as monoamine oxidase inhibitors and benzodiazepines.

引用

页码：544 / 561

页数：18

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