Quality of life and psychological well being in polycystic ovary syndrome

被引:257
作者
Barnard, L.
Ferriday, D.
Guenther, N.
Strauss, B.
Balen, A. H.
Dye, L.
机构
[1] Univ Leeds, Inst Psycholog Sci, Leeds LS2 9JT, W Yorkshire, England
[2] Univ Hosp, Inst Psychosocial Med & Psychotherapy, Jena, Germany
[3] Gen Infirm, Dept Reprod Med, Leeds LS1 3EX, W Yorkshire, England
关键词
depression; quality of life; polycystic ovary syndrome; acne; infertility;
D O I
10.1093/humrep/dem108
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Polycystic ovary syndrome (PCOS) is associated with poor quality of life (QoL) and high levels of depression. Existing research is confounded by small sample sizes and inconsistent use of control groups. METHODS: Depression and QoL were assessed in women with PCOS and healthy controls (n = 1359). The polycystic ovary syndrome health-related QoL questionnaire (PCOSQ) was modified to include an acne subscale. RESULTS: Seventy-one percentage of women with PCOS who were taking anti-androgen (AA) medication and 67% not taking AA medication were classified as depressed. Women with PCOS had lower QoL on all seven factors of the modified PCOSQ (emotional disturbance, weight, infertility, acne, menstrual symptoms, menstrual predictability and hirsutism). Weight was the largest contributor to poor QoL for women taking and not taking AA medication. Women taking AA medication, independent of diagnosis, generally had better QoL than women not taking them. CONCLUSIONS: This large study refines our understanding of depression and QoL in PCOS and demonstrates the need to regularly review the psychological health of women with PCOS.
引用
收藏
页码:2279 / 2286
页数:8
相关论文
共 48 条
[1]  
*AM PYSCH ASS, 1999, DIAGN STAT MAN MENT
[2]   What is polycystic ovary syndrome? Are national views important? [J].
Balen, A ;
Michelmore, K .
HUMAN REPRODUCTION, 2002, 17 (09) :2219-2227
[3]  
Balen AH, 2007, POLYCYSTIC OVARY SYNDROME, 2ND EDITION, P177
[4]   Should obese women with polycystic ovary syndrome receive treatment for infertility? Given the risks such women will face in pregnancy, they should lose weight first [J].
Balen, AH ;
Dresner, MT ;
Scott, EM ;
Drife, JO .
BRITISH MEDICAL JOURNAL, 2006, 332 (7539) :434-435
[5]  
Beck A. T., 1996, BDI-II: Beck Depression Inventory-II Manual, V2th ed.
[6]   An assessment of the generalizability of internet surveys [J].
Best, SJ ;
Krueger, B ;
Hubbard, C ;
Smith, A .
SOCIAL SCIENCE COMPUTER REVIEW, 2001, 19 (02) :131-145
[7]  
Borenstein J, 2003, J REPROD MED, V48, P79
[8]   Using the Internet to conduct surveys of health professionals: a valid alternative? [J].
Braithwaite, D ;
Emery, J ;
de Lusignan, S ;
Sutton, S .
FAMILY PRACTICE, 2003, 20 (05) :545-551
[9]   A randomized controlled trial of laser treatment among hirsute women with polycystic ovary syndrome [J].
Clayton, WJ ;
Lipton, M ;
Elford, J ;
Rustin, M ;
Sherr, L .
BRITISH JOURNAL OF DERMATOLOGY, 2005, 152 (05) :986-992
[10]   Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS) [J].
Cronin, L ;
Guyatt, G ;
Griffith, L ;
Wong, E ;
Azziz, R ;
Futterweit, W ;
Cook, D ;
Dunaif, A .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (06) :1976-1987