Synthesis of monoterpenic analogues of puupehenone and puupehedione

被引：22

作者：

Barrero, AF ^{[1
]}

Alvarez-Manzaneda, EJ ^{[1
]}

Herrador, MM ^{[1
]}

Valdivia, MV ^{[1
]}

Chahboun, R ^{[1
]}

机构：

[1] Univ Granada, Fac Ciencias, Dept Quim Organ, E-18071 Granada, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(98)00216-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Compounds 7-8, monoterpenic analogues of the marine metabolites puupehenone (1) and puupehedione (2), were prepared from the easily available beta-cyclocitral (10) and the aryllithium derived from 11 and 12. 8 showed antitumoral activity 4-10 times higher than that for the natural products. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2425 / 2428

页数：4

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