Utilization of Chimeric Antigen Receptor T-cell Therapy in Adults

被引:5
作者
Dudley, Channing Vail [1 ]
Baer, Brittney [1 ]
Simons, Rhea Micci [1 ]
机构
[1] Vanderbilt Ingram Canc Ctr, Hematol Oncol Program, 3322 West End Ave,Suite 1000, Nashville, TN 37203 USA
关键词
Chimeric antigen receptor (CAR) T cell; Cytokine release syndrome; Kymriah; Tisagenlecleucel; Yescarta; Axicabtagene ciloleucel; Patient management; MANAGEMENT;
D O I
10.1016/j.soncn.2019.08.009
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: To discuss the mechanism of action and nursing care of adults receiving chimeric antigen receptor (CAR) T-cell therapy. Data Source: Peer reviewed articles and pharmaceutical drug labels. Conclusion: CAR T-cell therapy is among the most exciting therapies in the evolution of cancer treatment. The efficacy of research with CAR T-cell therapy has shown promising results in hematologic malignancies as well as in solid tumors. Implications for Nursing Practice: Understanding the complexity of care for these patients from the bedside to the outpatient setting is vital for their survival and quality of care. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页数:4
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