Risks and Benefits of Weight Loss in Heart Failure

被引:10
作者
Lavie, Carl J. [1 ,2 ,3 ]
Alpert, Martin A. [4 ]
Ventura, Hector O. [1 ]
机构
[1] Univ Queensland, Sch Med, Ochsner Clin Sch, Dept Cardiovasc Dis,John Ochsner Heart & Vasc Ins, New Orleans, LA 70121 USA
[2] Univ Queensland, Sch Med, Ochsner Clin Sch, Exercise Labs,John Ochsner Heart & Vasc Inst, New Orleans, LA 70121 USA
[3] Louisiana State Univ Syst, Dept Prevent Med, Pennington Biomed Res Ctr, Baton Rouge, LA 70808 USA
[4] Univ Missouri, Hlth Sci Ctr, Div Cardiovasc Med, Columbia, MO 65202 USA
关键词
Obesity; Heart failure; Cardiovascular disease; Weight loss; LEFT-VENTRICULAR FUNCTION; OBESITY PARADOX; CARDIAC-PERFORMANCE; IMPACT; PROGNOSIS; MORPHOLOGY; GEOMETRY; CACHEXIA; FITNESS; MASS;
D O I
10.1016/j.hfc.2014.08.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity adversely affects many cardiovascular disease (CVD) risk factors and increases the risk of most CVD, including heart failure (HF). HF is markedly increased in the setting of obesity. However, obese patients with HF have a better prognosis than lean patients with HF, which has been termed the obesity paradox. Therefore, the role of weight loss, which generally improves ventricular structure, systolic and diastolic ventricular function, and New York Heart Association functional class in HF, remains controversial. This article discusses the pros and cons of weight loss and differentiates purposeful (healthy) from nonpurposeful (unhealthy) weight loss.
引用
收藏
页码:125 / +
页数:9
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