Introduction and development. One way to divide the different regions of the frontal lobe is according to its connections with the thalamic regions. Each of these regions, with their own particular cytoarchitecture, phylogeny and ontogeny, are also involved in distinct cognitive functions. The dorsolateral prefrontal cortex enables plans of action to be developed and executed, and working memory, which is needed for most cognitive processing, is the driving force behind what we call the executive functions. The orbital cortex and its subcortical connections make up a circuit that allows attention to be held and directed through a series of inhibitory mechanisms; this in turn prevents interference by stimuli that are irrelevant for a particular purpose. Finally, the cingulate cortex plays a part in initiating actions, in the intentionality of responses and in focusing attention. Conclusions. A deeper knowledge of the mechanisms behind the workings of the frontal lobe can explain the clinical pictures that are observed in many of the pathologies that appear during infancy, such as attention deficit hyperactivity disorder.
机构:
Sorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
INSERM, U 1127, Paris, France
Inst Cerveau & Moelle Epiniere, PICNIC Lab, ICM, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Tandetnik, Caroline
Sohier, Elisa
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Sorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
INSERM, U 1127, Paris, France
Inst Cerveau & Moelle Epiniere, PICNIC Lab, ICM, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Sohier, Elisa
Capelle, Laurent
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Grp Hosp Pitie Salpetriere, AP HP, Dept Neurosurg, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Capelle, Laurent
du Boullay, Viviane
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Grp Hosp Pitie Salpetriere, AP HP, Dept Neurosurg, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
du Boullay, Viviane
Obadia, Michael
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Fdn Rothschild Hosp, Dept Neurol, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Obadia, Michael
Chammat, Mariam
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Sorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
INSERM, U 1127, Paris, France
Inst Cerveau & Moelle Epiniere, PICNIC Lab, ICM, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Chammat, Mariam
Pyatigorskaia, Nadya
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Sorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
INSERM, U 1127, Paris, France
Grp Hosp Pitie Salpetriere, AP HP, Dept Neuroradiol, Paris, France
Inst Cerveau & Moelle Epiniere, Aramis Team, ICM, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
Pyatigorskaia, Nadya
Naccache, Lionel
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Sorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
INSERM, U 1127, Paris, France
Inst Cerveau & Moelle Epiniere, PICNIC Lab, ICM, Paris, France
Grp Hosp Pitie Salpetriere, AP HP, Dept Neurol, Paris, France
Grp Hosp Pitie Salpetriere, AP HP, Dept Clin Neurophysiol, Paris, FranceSorbonne Univ, UPMC Univ Paris 06, Fac Med Pitie Salpetriere, Paris, France
机构:
Tel Aviv Univ, Sackler Fac Med, Emot Cognit Res Ctr, Shalvata Mental Hlth Care Ctr, Hod Hasharon, Israel
Ariel Univ Ctr Samaria, Dept Behav Sci, Ariel, IsraelHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA
Braw, Yoram
Aviram, Shai
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Tel Aviv Univ, Sackler Fac Med, Emot Cognit Res Ctr, Shalvata Mental Hlth Care Ctr, Hod Hasharon, IsraelHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA
Aviram, Shai
Bloch, Yuval
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Tel Aviv Univ, Sackler Fac Med, Emot Cognit Res Ctr, Shalvata Mental Hlth Care Ctr, Hod Hasharon, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA
Bloch, Yuval
Levkovitz, Yechiel
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Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA
Tel Aviv Univ, Sackler Fac Med, Emot Cognit Res Ctr, Shalvata Mental Hlth Care Ctr, Hod Hasharon, Israel
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat, Boston, MA 02114 USA
机构:
Capital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R ChinaCapital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China
Fang, Shengyu
Wang, Yinyan
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Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China
Wang, Yinyan
Jiang, Tao
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Capital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China
Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing, Peoples R China
Brain Tumor Ctr, Beijing Inst Brain Disorders, Beijing, Peoples R ChinaCapital Med Univ, Beijing Neurosurg Inst, Beijing, Peoples R China
机构:
Behavioural Neurology Program and Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, TorontoBehavioural Neurology Program and Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto
Chayer C.
Freedman M.
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Behavioural Neurology Program and Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, TorontoBehavioural Neurology Program and Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto