Molecular Analysis of Caprine Enterovirus Circulating in China during 2016-2021: Evolutionary Significance

被引:6
作者
Chang, Xiaoran [1 ]
Lin, Qian [1 ]
Zhang, Qun [1 ]
Hu, Junying [1 ]
Tursun, Gulbahar [1 ]
Deng, Yingrui [1 ]
Guo, Chunguang [1 ]
Wang, Xinping [1 ]
机构
[1] Jilin Univ, Coll Vet Med, Minist Educ, State Key Lab Zoonot Dis,Key Lab Zoonosis Res, Changchun 130012, Peoples R China
来源
VIRUSES-BASEL | 2022年 / 14卷 / 05期
基金
中国国家自然科学基金;
关键词
caprine; ovine enterovirus; CEV-JL14; phylogenetic analysis; genotype; evolution; alignment analysis; BOVINE; SEQUENCE;
D O I
10.3390/v14051051
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Here, we report the characterization of 13 novel caprine/ovine enterovirus strains isolated from different regions in China during 2016-2021. Immunoperoxidase monolayer assay showed that these viral strains shared strong cross-reaction with the previously reported caprine enterovirus CEV-JL14. Alignment analysis of the complete nucleotide sequences revealed 79.2%-87.8% and 75.0%-76.7% sequence identity of these novel caprine enterovirus strains to CEV-JL14 and TB4-OEV, respectively. Phylogenetic analyses clustered these novel strains to EV-G based on the amino acid sequences of P1 and 2C+3CD. Moreover, phylogenetic analysis of these caprine enterovirus strains identified three new EV-G types using VP1 sequences. These results demonstrate the genetic variations and the evolution of caprine enterovirus.
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页数:12
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