Spinal cord involvement in Behcet's disease

被引：23
作者：
Lee, Hyung Seok [1 ]
Kim, Do Young [2 ]
Shin, Ha Young [1 ]
Choi, Young-Chul [1 ]
Kim, Seung Min [1 ]
机构：
[1] Yonsei Univ, Coll Med, Dept Neurol, 50 Yonsei Ro, Seoul 120752, South Korea
[2] Yonsei Univ, Coll Med, Dept Dermatol, Seoul 120752, South Korea
来源：
MULTIPLE SCLEROSIS JOURNAL | 2016年 / 22卷 / 07期
关键词：
Behcet's disease; neuro-Behcet's disease; longitudinally extensive transverse myelitis; spinal cord; serum anti-aquaporin-4 antibody; neuromyelitis optica; EXTENSIVE TRANSVERSE MYELITIS; NEUROMYELITIS-OPTICA; CLINICAL CHARACTERISTICS; INFLIXIMAB;
D O I：
10.1177/1352458515613642
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: Spinal cord involvement in Behcet's disease is not well studied. Objective: To evaluate the clinical, laboratory and magnetic resonance imaging characteristics of spinal cord involvement in Behcet's disease. Methods: We retrospectively reviewed 10 spinal cord involvements in seven patients with Behcet's disease. Results: The median age of onset for spinal cord involvement was 32 (23-45 years). Two patients showed a secondary progressive course. Cerebrospinal fluid findings revealed mild to moderate pleocytosis and/or elevated protein levels. In eight spinal cord involvements, the lesion was longer than three vertebrae. Serum anti-aquaporin-4 antibody was negative in all four patients tested. Conclusions: Longitudinally extensive transverse myelitis is a characteristic manifestation of spinal cord involvement in Behcet's disease.
引用
收藏
页码：960 / 963
页数：4
相关论文
共 10 条
  • [1] Neuro-Behcet's disease: epidemiology, clinical characteristics, and management
    Al-Araji, Adnan
    Kidd, Desmond P.
    [J]. LANCET NEUROLOGY, 2009, 8 (02) : 192 - 204
  • [2] Longitudinally extensive transverse myelitis as the sole presentation of neuro-Behcet's disease responding to infliximab
    Coulter, Ian
    Huda, Saif
    Baborie, Atik
    Jacob, Anu
    [J]. JOURNAL OF SPINAL CORD MEDICINE, 2012, 35 (02) : 122 - 124
  • [3] Subacute Longitudinal Myelitis Associated with Behcet's Disease
    Fukae, Jiro
    Noda, Kazuyuki
    Fujishima, Kenji
    Takahashi, Toshiyuki
    Hattori, Nobutaka
    Okuma, Yasuyuki
    [J]. INTERNAL MEDICINE, 2010, 49 (04) : 343 - 347
  • [4] International Study Group for Beh~et's Disease, 1990, LANCET, V335, P1078, DOI DOI 10.1016/0140-
  • [5] Efficacy of infliximab in neuro-Behcet's disease presenting with isolated longitudinally extensive transverse myelitis
    Kuroda, Ryo
    Suzuki, Junko
    Muramatsu, Mizuho
    Tasaki, Asami
    Yano, Mariko
    Imai, Noboru
    Serizawa, Masahiro
    Kobari, Masahiro
    [J]. JOURNAL OF NEUROLOGY, 2013, 260 (12) : 3167 - 3170
  • [6] Magnetic resonance imaging in neuromyelitis optica
    Tackley, George
    Kuker, Wilhelm
    Palace, Jacqueline
    [J]. MULTIPLE SCLEROSIS JOURNAL, 2014, 20 (09) : 1153 - 1164
  • [7] Longitudinal extensive transverse myelitis-it's not all neuromyelitis optica
    Trebst, Corinna
    Raab, Peter
    Voss, Elke Verena
    Rommer, Paulus
    Abu-Mugheisib, Mazen
    Zettl, Uwe K.
    Stangel, Martin
    [J]. NATURE REVIEWS NEUROLOGY, 2011, 7 (12) : 688 - 698
  • [8] Recurrent longitudinal extensive transverse myelitis in a neuro-Behcet syndrome treated with infliximab
    Uygunoglu, Ugur
    Pasha, Maarya
    Saip, Sabahattin
    Siva, Aksel
    [J]. JOURNAL OF SPINAL CORD MEDICINE, 2015, 38 (01) : 111 - 114
  • [9] A secondary progressive clinical course is uncommon in neuromyelitis optica
    Wingerchuk, D. M.
    Pittock, S. J.
    Lucchinetti, C. F.
    Lennon, V. A.
    Weinshenker, B. G.
    [J]. NEUROLOGY, 2007, 68 (08) : 603 - 605
  • [10] Clinical characteristics and course of spinal cord involvement in Behcet's disease
    Yesilot, N.
    Mutlu, M.
    Gungor, O.
    Baykal, B.
    Serdaroglu, P.
    Akman-Demir, G.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2007, 14 (07) : 729 - 737
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