Studies of phospholipid monolayer at liquid/liquid interface in presence of an antimicrobial peptide

被引：12
|
作者：
Saint Martin, E.
Konovalov, O.
Daillant, J.
机构：
[1] European Synchrotron Radiat Facil, F-38043 Grenoble 9, France
[2] CEA Saclay, LIONS, F-91191 Gif Sur Yvette, France
来源：
THIN SOLID FILMS | 2007年 / 515卷 / 14期
关键词：
bending rigidity; Langmuir-Blodgett films; X-ray scattering; liquid-liquid interface;
D O I：
10.1016/j.tsf.2006.12.010
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
An application of the antimicrobial peptides (AP) as antibiotics of new generation requires comprehensive studies of the interaction of these peptides with a cell membrane (CM). Despite the big progress in characterization of the AP-CM system, its elastic properties remain unclear. In the present work we present studies of the structure and the bending rigidity of phospholipid monolayers formed at hexadecane/water interface in presence or absence of antimicrobial peptides. It is shown that due to the interactions between the monolayer and the peptide, the bending rigidity decreases after the injection of the peptide. (c) 2006 Elsevier B.V. All rights reserved.
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页码：5687 / 5690
页数：4
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